Solid-state fermentation: a promising microbial technology for secondary metabolite production

Applied Microbiology and Biotechnology
T RobinsonP Nigam

Abstract

Solid state (substrate) fermentation (SSF) has been used successfully for the production of enzymes and secondary metabolites. These products are associated with the stationary phase of microbial growth and are produced on an industrial scale for use in agriculture and the treatment of disease. Many of these secondary metabolites are still produced by submerged liquid fermentations (SmF) even though production by this method has been shown to be less efficient than SSF. As large-scale production increases further, so do the costs and energy demands. SSF has been shown to produce a more stable product, requiring less energy, in smaller fermenters, with easier downstream processing measures. In this article we review an important area of biotechnology, since the recent evidence indicates that bacteria and fungi, growing under SSF conditions, are more than capable of supplying the growing global demand for secondary metabolites.

Citations

Jan 17, 2007·Applied Microbiology and Biotechnology·Rojan P JohnAshok Pandey
Oct 13, 2009·Applied Microbiology and Biotechnology·Javier Barrios-González, Roxana U Miranda
Oct 4, 2011·Current Microbiology·Jorge William Arboleda ValenciaMaria Fatima Grossi-de-Sa
May 11, 2010·Bioprocess and Biosystems Engineering·Michele Rigon SpierCarlos Ricardo Soccol
Jan 24, 2006·Journal of Industrial Microbiology & Biotechnology·Punyasloke BhaduryPhillip C Wright
May 9, 2006·Journal of Industrial Microbiology & Biotechnology·Ramunas BigelisMichael Greenstein
Jun 9, 2009·Journal of Industrial Microbiology & Biotechnology·Dasagrandhi ChakradharAvinash P Sattur
Nov 28, 2009·Applied Biochemistry and Biotechnology·Betânia H LunelliRubens Maciel Filho
Apr 14, 2011·Applied Biochemistry and Biotechnology·V VivekanandRajesh P Singh
Jun 9, 2005·Current Opinion in Microbiology·Udo Hölker, Jürgen Lenz
Nov 23, 2007·Natural Product Reports·Dwight D BakerVineet Rajgarhia
Dec 4, 2003·Chemical & Pharmaceutical Bulletin·Takuya ItohMotomasa Kobayashi
Oct 6, 2005·The Journal of General and Applied Microbiology·Nisha K Rana, Tej K Bhat
May 5, 2007·Prikladnaia biokhimiia i mikrobiologiia·J LiuJ C Yang
Sep 24, 2013·Applied and Environmental Microbiology·Elham AslankoohiKevin J Verstrepen
Aug 1, 2007·Journal of Industrial Microbiology & Biotechnology·Kizhakkedathu Narayanan NiladeviParukuttyamma Prema
Jun 4, 2013·Journal of Bioscience and Bioengineering·Kazunari ItoTsuyoshi Miyake
Jan 2, 2016·Bioresource Technology·Juliana Vasco-CorreaYebo Li
Jul 23, 2011·Journal of Bioscience and Bioengineering·Luís AbrunhosaJosé António Teixeira
Dec 18, 2010·Journal of Bioscience and Bioengineering·Kazunari ItoTsuyoshi Miyake
Jul 22, 2009·Journal of Bioscience and Bioengineering·Jesús G BañosJavier Barrios-González
Apr 2, 2016·Bioresource Technology·Chul Woo NamJong Moon Park
Apr 20, 2006·Bioresource Technology·M C Cammarota, D M G Freire
Jun 5, 2013·Asian Pacific Journal of Tropical Biomedicine·Gebreselema GebreyohannesNagappan Raja
Nov 22, 2016·Bioscience, Biotechnology, and Biochemistry·Hyun ChungYoung-Suk Kim
Jun 29, 2004·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Chunhua Lu, Yuemao Shen
Sep 28, 2018·Journal of Industrial Microbiology & Biotechnology·Chiraz Soumia M AmrineNicholas H Oberlies
Feb 25, 2009·Prikladnaia biokhimiia i mikrobiologiia·N A UshakovaA V Nifatov

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