Solitary Extrahepatic Intramuscular Metastasis from Cryptogenic Hepatocellular Carcinoma

ACG Case Reports Journal
Talhah ZubairGordon Gao

Abstract

Although hepatocellular carcinoma (HCC) recurrence after curative resection is not uncommon, it primarily recurs in the liver prior to metastatic progression. We report a case of resected pT2N0 cryptogenic HCC that recurred in the superior paracervical musculature without evident intrahepatic recurrence. The patient also developed cervical spine instability requiring urgent neurosurgery. Cryptogenic HCC is thought to arise from non-alcoholic fatty liver disease even without cirrhosis. Unfortunately, it also portends a worse prognosis compared to HCC of other etiologies. This highlights the aggressive behavior of cryptogenic HCC, which warrants further research as non-alcoholic fatty liver disease becomes increasingly common.

References

Dec 4, 2010·International Journal of Cancer. Journal International Du Cancer·Judith ErtleAli Canbay
Dec 15, 2010·Gut·Olivier FargesValérie Paradis
Sep 6, 2013·Annals of Surgical Oncology·Ioannis HatzarasTimothy M Pawlik
May 5, 2017·World Journal of Hepatology·George CholankerilSanjaya K Satapathy
Aug 26, 2017·World Journal of Hepatology·Kazuhiro TakahashiDean Y Kim
Oct 19, 2017·Liver International : Official Journal of the International Association for the Study of the Liver·Tomi W JunMindie H Nguyen
Jan 2, 2018·World Journal of Clinical Oncology·Adnan Said, Aiman Ghufran

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Methods Mentioned

BETA
dissection
biopsy

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Carcinoma, Hepatocellular

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