PMID: 15227752Jul 1, 2004Paper

Solitary fibrous tumor of the urinary bladder

Yonsei Medical Journal
Se Hoon KimNam Hoon Cho

Abstract

Solitary fibrous tumor (SFT) is a distinct spindle cell tumor arising mainly in the pleura, however, SFT of extra-pleural sites had been reported. To our knowledge, five cases of the urinary bladder SFT had been reported. We have recently experienced a case of SFT of the urinary bladder in a 56-year- old man who was admitted to the hospital with a 4-month history of voiding difficulty, frequency, and residual urine sensation. A computerized tomography scan revealed a 12cm sized intravesical mass. The mass was marginally excised under the impression of it being a benign spindle cell tumor by pre-operative needle biopsy. On gross examination, the mass was multinodular, creamy white, and the cut surface was fibrotic with a rubbery consistency. Microscopic examination revealed haphazardly arranged spindle cells with a lace-like deposition of inter- and pericellular collagen. Areas of increased cellularity show nuclear atypia and occasional mitoses (2-3/10HPF). The immunohistochemical staining revealed an intense CD34 and bcl-2 immunoreactivity. Although the exact biologic behavior of these tumors has not been clarified, most of the reported cases have undergone a benign clinical course.

Citations

Mar 22, 2006·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jade J Wong-You-CheongIsabell A Sesterhenn
Jan 25, 2011·AJR. American Journal of Roentgenology·Sung Bin ParkKyoung-Sik Cho
Jun 18, 2010·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Tao WangZhangqun Ye
Sep 20, 2012·Journal of the Chinese Medical Association : JCMA·Shih-Hao ChengChen-Li Cheng
Dec 20, 2012·Pathology·Fabio TavoraJonathan I Epstein
Nov 1, 2016·Case Reports in Urology·Eduardo Yukio TanakaMarcus Vinicius Sadi
May 29, 2007·The American Journal of Surgical Pathology·Mehsati Herawi, Jonathan I Epstein
Nov 6, 2012·Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology·Cong WangToshitsugu Oka
Mar 22, 2013·International Journal of Surgical Pathology·Cinzia SpairaniGian Luigi Bigatti

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