Solitary fibrous tumour of pleura: CT differentiation of benign and malignant types

Clinical Radiology
A GuptaJ M Seely

Abstract

To analyse and compare the computed tomography (CT) features of benign and malignant types of histopathologically proven cases of solitary fibrous tumours of pleura (SFTP). Retrospective analysis of preoperative CT images of 28 cases of histopathologically proven and classified SFTP from three participating institutions was performed. Patient demographics and lesion characteristics including size, borders, presence of a pedicle, extension into the fissure, attenuation, enhancement, pleural effusion, and calcifications were recorded and correlated with the final histopathological diagnosis. Type and results of preoperative biopsy were also recorded. Follow-up imaging and the clinical charts were reviewed to identify recurrence. Out of 28 cases (15 women and 13 men), 18 were proven to be benign and 10 were malignant. The mean age of patients was 58.1±15.9 and 66.5±11.8 years (p=0.1564) for benign and malignant tumours, respectively. The median (interquartile range) diameter was 6.05 (3.2-10.9) cm for benign and 15.7 (7.1-17.5) cm for malignant type tumours (p=0.0291). Tumours had lobulate borders in 28% (5/18) of benign cases and in 80% (8/10) of malignant cases (p=0.0163). Extension into adjacent fissure was seen in 22% (4/18) o...Continue Reading

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Citations

Jan 30, 2018·The Journal of International Medical Research·Yong-Hao YouYi Zhang
Apr 23, 2020·Medicina·Cornel SavuNicolae Bacalbasa
Aug 25, 2020·ERJ Open Research·Rachel M MercerNajib M Rahman
Feb 15, 2020·Journal of Cancer Research and Clinical Oncology·Chao ZhouJikai Zhao

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