Solitary metastases and high-grade gliomas: radiological differentiation by morphometric analysis and perfusion-weighted MRI

Clinical Radiology
Bahattin HakyemezMufit Parlak

Abstract

To evaluate the value of morphometric analysis and perfusion-weighted magnetic resonance imaging (MRI) in differentiating solitary metastases from high-grade gliomas. Forty-eight tumours (22 high-grade gliomas and 26 solitary hemispheric metastases) were evaluated using conventional and perfusion-weighted MRI. T2-weighted, gradient-echo, echo-planar sequences were used for perfusion-weighted MRI. Relative cerebral blood volume (rCBV) ratios were calculated by dividing the rCBV of the intratumoural and peritumoural areas with the average CBV value of the normal white matter areas. Morphometric analysis was carried out by proportioning the area of peritumoural oedema to the mass area. Mann-Whitney U test and ROC curve analysis were applied for statistical analysis. P<0.05 was accepted as statistically significant. Mean rCBV ratios of intratumoural areas of high-grade gliomas and metastases were 5.02+/-2.47 and 4.62+/-2.46, respectively. No statistically significant difference was found (p=0.515). rCBV ratios of peritumoural oedema were 0.89+/-0.51 in high-grade gliomas and 0.31+/-0.12 in metastases. The difference was statistically significant (p<0.001). According to the results of morphometric analysis, a statistically significa...Continue Reading

References

Jul 1, 1979·Journal of Neurosurgery·D M Long
Mar 1, 1981·Stroke; a Journal of Cerebral Circulation·K A Hossman, M Blöink
Jan 1, 1993·Topics in Magnetic Resonance Imaging : TMRI·D Le BihanM Fulham

❮ Previous
Next ❯

Citations

Sep 1, 2012·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·S J MillsA Jackson
Dec 3, 2014·Neurologic Clinics·Thomas J PfiffnerLaszlo Mechtler
Oct 31, 2012·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Ioannis TsougosEftychia Kapsalaki
Jul 18, 2015·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Pawel SzwarcEwa Pietka
Nov 27, 2010·Neurosurgery Clinics of North America·Angela Lignelli, Alexander G Khandji
Jan 8, 2014·Journal of Magnetic Resonance Imaging : JMRI·Christophe VandendriesGuillaume Saliou
Jul 30, 2015·Clinical Neuroradiology·A Radbruch, M Bendszus
Mar 21, 2015·The Veterinary Journal·R Timothy Bentley
May 6, 2015·Current Problems in Cancer·Stephen F KralikChang Y Ho
May 30, 2013·Surgical Neurology International·Michael R LevittDaniel L Silbergeld
May 30, 2013·Surgical Neurology International·Kathleen R Fink, James R Fink
Sep 5, 2018·Clinical Nuclear Medicine·Xiaoxia XuZhi Yang
Jan 23, 2015·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Patricia SvolosIoannis Tsougos
Mar 14, 2020·Journal of Magnetic Resonance Imaging : JMRI·Andreas Voskrebenzev, Jens Vogel-Claussen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved