Solitary metastatic clear cell carcinoma to the spleen.

Rare Tumors
Mohamed A ZayedSherry M Wren

Abstract

A 57-year-old with a 9-year history of increased abdominal girth, presented with increased abdominal pain, anemia, and acute renal failure. His past medical history was only remarkable for a previous lung cancer 21 years ago that was treated with a right upper lung lobectomy. A computed tomography (CT) scan of the patient's abdomen showed a solitary 20×20×25cm cystic splenic mass. The patient underwent an urgent splenectomy. Intra-operatively a large splenic cystic cavity was found with a solid inferior splenic mass. An exhaustive histological analysis of the splenic mass confirmed a clear cell carcinoma with low malignant potential that likely represented a metastatic lesion from the patient's previous distant lung cancer. Postoperatively the patient recovered well and at 1-year followup the patient demonstrated no further evidence of metastatic disease. This case is extremely unique and provides a very rare example of a metastatic solitary clear cell carcinoma to the spleen, with a presumed latency period of more than 20 years.

References

Oct 1, 1992·Southern Medical Journal·P J CapizziJ E Skandalakis
Mar 1, 1990·The American Journal of Surgical Pathology·M J GaffeyT V Colby
Nov 1, 1991·Gynecologic Oncology·M MorrisF N Rutledge
Jul 1, 1991·European Journal of Radiology·C GoergK Goerg
Dec 1, 1989·Gynecologic Oncology·E W SonnendeckerK A Margolius
Jul 1, 1986·Clinical Nuclear Medicine·J D SlavinR P Spencer
Aug 1, 1985·Journal of Clinical Pathology·C Edwards, A Carlile
Jun 1, 1985·World Journal of Surgery·L MorgensternS A Geller
Aug 1, 1995·Gynecologic Oncology·J L NicklinL P Havenar
Mar 1, 1993·Gynecologic Oncology·R Farias-EisnerJ S Berek
Jan 1, 1997·The British Journal of Surgery·K S Mainprize, A R Berry
Mar 4, 1999·Gynecologic Oncology·M L GemignaniR R Barakat
Apr 4, 2000·Archives of Pathology & Laboratory Medicine·K Y Lam, V Tang
Dec 21, 2000·Pathology International·A IyodaH Ohwada
Jul 1, 1963·American Journal of Clinical Pathology·J H MARYMONT, S GROSS
Mar 27, 2004·Southern Medical Journal·Brian J Schmidt, Stephen L Smith
Jan 1, 1950·Cancer·H L ABRAMSN GOLDSTEIN
Oct 11, 2005·The Journal of Thoracic and Cardiovascular Surgery·Juan C GarzonAnthony P C Yim
Jul 29, 2006·Pathology International·Yoshin AdachiKazuhiko Hayashi
Dec 23, 2006·The Annals of Thoracic Surgery·Alpha M KavunkalVijit Koshy Cherian
Apr 30, 2008·World Journal of Surgical Oncology·Christos MarkopoulosHelen Gogas
Sep 24, 2008·Acta chirurgica Belgica·I Van HulR Rutsaert
Mar 24, 2009·Archives of Gynecology and Obstetrics·Benjamin PiuraRuthy Shaco-Levy
May 5, 2010·International Journal of Surgery·Benedetto IelpoGiuseppe Petrella

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BETA
biopsy

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