Solitary myofibroma of the lumbar vertebra: adult case.

Skeletal Radiology
E KonishiA Yanagisawa

Abstract

We present the first known adult case of solitary myofibroma of bone, which affected a lumbar vertebra in a 33-year-old male. Radiography identified a purely lytic lesion with a sclerotic rim in the right pedicle of L1. CT showed an expansile lytic lesion with a sclerotic rim. MRI of the lesion revealed an isointense signal on T1-weighted images, an inhomogeneously hyperintense signal on T2-weighted images, and marked enhancement with gadolinium. Pathological study showed a mixed picture of nodular proliferation of spindle-shaped myoid cells and hemangiopericytomatous proliferation of short spindle/small round cells. The tumor cells were immunoreactive for smooth muscle actin and immunonegative for desmin. This case of solitary myofibroma of bone is exceptionally rare because of its occurrence in an adult older than 20 years of age and its location at an extra-craniofacial site.

References

Jan 1, 1992·Oral Surgery, Oral Medicine, and Oral Pathology·N VigneswaranC A Waldron
Mar 1, 1990·Neurologia Medico-chirurgica·T KuroiwaA Tsutsumi
Oct 1, 1991·The American Journal of Surgical Pathology·C Y InwardsT C Shives
Sep 1, 1990·Zeitschrift für Orthopädie und ihre Grenzgebiete·W F BeyerA R Goldmann
Oct 1, 1989·The American Journal of Surgical Pathology·Y DaimaruM Enjoji
Apr 1, 1984·Journal of Maxillofacial Surgery·P J Slootweg, H Müller
Oct 15, 1981·Cancer·E B Chung, F M Enzinger
Oct 1, 1994·Journal of Neurosurgery·M J RutiglianoA L Albright
Jan 1, 1994·Spine·R AsirvathamJ I Antonius
Mar 1, 1993·The American Journal of Surgical Pathology·T HasegawaH Nakanishi
Nov 21, 1998·Archives of Ophthalmology·C L ShieldsR C Eagle
Jun 1, 1999·Journal of Neurosurgery·P W DetwilerH L Rekate
Sep 15, 1999·Skeletal Radiology·S ImaizumiI Emura
Feb 9, 2000·European Radiology·K OkamotoS Tokiguchi
May 3, 2000·Pathology International·T YamamotoK Hanioka
Sep 1, 1954·Cancer·A P STOUT
Jan 15, 2004·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Masayuki TsujiYoshiko Uemura
Oct 21, 2004·Annals of Diagnostic Pathology·Parish P SedghizadehSaul Suster
Nov 24, 2004·Pediatric Radiology·Khaldoun KoujokRamiro J Hernandez
Sep 27, 2005·Clinical & Experimental Ophthalmology·Dong Heun NamSe Hyun Baek

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Citations

Oct 11, 2014·Journal of Neurosurgery. Spine·Benjamin M DaviesKanna K Gnanalingham
Sep 4, 2015·Hand : Official Journal of the American Association for Hand Surgery·Yihong MaShi Wei

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