Solitary pleural plasmacytomas manifested as a massive pleural effusion without evidence of monoclonal gammopathy

Respirology : Official Journal of the Asian Pacific Society of Respirology
Po Hao FengYing-Huang Tsai

Abstract

The majority of extramedullary plasmacytomas involve the upper respiratory tract but only a few are associated with serum monoclonal gammopathy. Most extramedullary plasmacytomas respond to local radiotherapy and have a better prognosis than multiple myeloma. Solitary plasmacytomas, involving the pleura, are very rare. This case report describes a patient with a solitary extramedullary plasmacytoma involving the pleura, and no evidence of serum, urine or pleural fluid paraproteins. Diagnosis was made by strongly positive immunohistochemical stains with CD38, CD138 and MUM-1 of the pleural tumour. The response to both radiotherapy and chemotherapy was poor and the patient died shortly after diagnosis.

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Citations

Jun 26, 2012·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·H Ben SalahJ Daoud
Jun 11, 2020·British Journal of Haematology·Kheng-Wei YeohGeorge Mikhaeel
Dec 22, 2016·Oncoimmunology·Djordje AtanackovicTim Luetkens

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