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Solubilization and stabilization of the cytotoxic agent coralyne

Journal of Pharmaceutical Sciences

Nov 1, 1975

M J ChoI H Pitman

PMID: 481

Abstract

Kinetic studies were carried out on the ring opening of the quaternary nitrogen cation, coralynium ion (I), to yield 6'-acetylpapaverine (III), on the cyclization of III to yield I, and on a photochemical reaction undergone by I in aqueous solutions exposed to visible light. From the re...read more

Mentioned in this Paper

Antineoplastic Agents
Drug Formulation Process
Coralyne
Coralyne chloride
Cations
Spectrophotometry, Ultraviolet
Freeze Drying
Drug Stability
Chloride Measurement
Photochemistry
Paper Details
References

Solubilization and stabilization of the cytotoxic agent coralyne

Journal of Pharmaceutical Sciences

Nov 1, 1975

M J ChoI H Pitman

PMID: 481

DOI:

Abstract

Kinetic studies were carried out on the ring opening of the quaternary nitrogen cation, coralynium ion (I), to yield 6'-acetylpapaverine (III), on the cyclization of III to yield I, and on a photochemical reaction undergone by I in aqueous solutions exposed to visible light. From the re...read more

Mentioned in this Paper

Antineoplastic Agents
Drug Formulation Process
Coralyne
Coralyne chloride
Cations
Spectrophotometry, Ultraviolet
Freeze Drying
Drug Stability
Chloride Measurement
Photochemistry

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