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Solubilization and stabilization of the cytotoxic agent coralyne

Journal of Pharmaceutical Sciences

Nov 1, 1975

M J ChoI H Pitman

PMID: 481

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Abstract

Kinetic studies were carried out on the ring opening of the quaternary nitrogen cation, coralynium ion (I), to yield 6'-acetylpapaverine (III), on the cyclization of III to yield I, and on a photochemical reaction undergone by I in aqueous solutions exposed to visible light. From the re...read more

Mentioned in this Paper

Antineoplastic Agents
Cations
Drug Stability
Drug Formulation Process
Salts
Coralyne chloride
Berberine Alkaloids
Hydrogen-Ion Concentration
Spectrophotometry, Ultraviolet
Cytotoxic agent
Paper Details
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  • Solubilization and stabilization of the cytotoxic agent coralyne

    Journal of Pharmaceutical Sciences

    Nov 1, 1975

    M J ChoI H Pitman

    PMID: 481

    DOI:

    Abstract

    Kinetic studies were carried out on the ring opening of the quaternary nitrogen cation, coralynium ion (I), to yield 6'-acetylpapaverine (III), on the cyclization of III to yield I, and on a photochemical reaction undergone by I in aqueous solutions exposed to visible light. From the re...read more

    Mentioned in this Paper

    Antineoplastic Agents
    Cations
    Drug Stability
    Drug Formulation Process
    Salts

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