Soluble eggshell membrane: A natural protein to improve the properties of biomaterials used for tissue engineering applications

Materials Science & Engineering. C, Materials for Biological Applications
Mahesh Kumar Sah, S N Rath


Extracellular matrix (ECM) acts as an instructing template for the cells contained in tissues. It plays a vital role in regulating cellular behavior by holding and interacting with various growth factors and signaling molecules. The ECM materials are either directly derived from a natural origin, or synthesized mimicking the natural ECM. In this review, we have addressed the ECM derived from eggshell membrane (ESM). The development of porous structures from natural biopolymers, such as ESM holds a number of advantages for tissue engineering applications. By using ESM in tissue engineering application, the cells attach and function to make a required tissue. Thereafter, the scaffold provides mechanical support as well as a platform for cellular interaction, hence, forming a fully functional tissue. The present review summarizes the structure-function relationship of ESM and advancement in its processing methods; the contribution of its soluble form (soluble eggshell membrane protein, SEP) in the development of promising hybrid biomaterials; and the recent advancement of their applications. In addition, this comprehensive review highlights the use of ESM for guided tissue regeneration; promising future applications of SEP in tiss...Continue Reading


Feb 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·A E PostlethwaiteA H Kang
Apr 1, 1992·Matrix : Collagen and Related Research·U B LaurentT C Laurent
Nov 1, 1991·Matrix : Collagen and Related Research·J I AriasA I Caplan
Aug 1, 1991·The Journal of Cell Biology·A P KwanM E Grant
Jan 1, 1991·Connective Tissue Research·J I AriasA I Caplan
Jun 1, 1989·The Anatomical Record·A R PooleE R Lee
Aug 19, 1971·Biochimica Et Biophysica Acta·C I Osuoji
Jun 1, 1972·Chemical Reviews·D R Williams
Jan 1, 1969·Zeitschrift für Zellforschung und mikroskopische Anatomie·R Bellairs, A Boyde
Jan 1, 1984·Journal of Cellular Biochemistry·F Grinnell
Jul 1, 1984·Developmental Biology·M WongR Stern
Jan 1, 1980·Connective Tissue Research·B C Starcher, G S King
Jun 1, 1984·Molecular and Cellular Biology·O CapassoR Cancedda
Jan 8, 1981·Biochimica Et Biophysica Acta·G CrombieC Franzblau
May 1, 1982·Burns, Including Thermal Injury·K Maeda, Y Sasaki
Oct 1, 1980·Chemical & Pharmaceutical Bulletin·M WashitakeI Tanaka
Apr 21, 1995·Annals of the New York Academy of Sciences·A L Boskey
Feb 1, 1995·Matrix Biology : Journal of the International Society for Matrix Biology·T M WuA H Heuer
Jan 1, 1995·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·G D WalkerT R Oegema
Oct 1, 1993·The Journal of Clinical Investigation·Cecilia M GiachelliS M Schwartz
Jul 16, 1996·Biochemical and Biophysical Research Communications·G J RucklidgeS P Robins
Aug 1, 1996·Bioscience, Biotechnology, and Biochemistry·K TakahashiM Hattori
Jan 1, 1996·Connective Tissue Research·D A CarrinoA I Caplan
Apr 1, 1997·Matrix Biology : Journal of the International Society for Matrix Biology·M S FernandezJ L Arias
Jan 1, 1997·Connective Tissue Research·J I AriasA I Caplan
Apr 29, 1998·The Journal of Clinical Investigation·L LiawB L Hogan
Apr 29, 1998·Journal of Biomaterials Science. Polymer Edition·K YamauchiT Mori
Jun 20, 1998·The Journal of Cell Biology·M ScatenaCecilia M Giachelli
Oct 21, 1998·Microsurgery·K K WangC L Cetrulo
Nov 3, 1998·Cell and Tissue Research·A Pilloni, G W Bernard
Jul 10, 1999·Applied Biochemistry and Biotechnology·Shin-ichi IshikawaI Satoh
Nov 11, 1999·Biochimica Et Biophysica Acta·M AkagawaKyozo Suyama
Apr 25, 2000·Biophysical Journal·D WilsonD Kaplan
Sep 12, 2000·Matrix Biology : Journal of the International Society for Matrix Biology·Maxwell T HinckeYves Nys
Nov 9, 2000·Immunology Today·A W O'ReganJ S Berman
Dec 5, 2000·Matrix Biology : Journal of the International Society for Matrix Biology·Cecilia M Giachelli, S Steitz
Dec 5, 2000·Matrix Biology : Journal of the International Society for Matrix Biology·J E DennisA I Caplan
Feb 27, 2001·Matrix Biology : Journal of the International Society for Matrix Biology·M Soledad FernandezJ I Arias
Apr 21, 2001·The Journal of Craniofacial Surgery·L DupoirieuxL Téot
May 25, 2001·Poultry Science·T NakanoL Ozimek
Jan 22, 2002·Bioresource Technology·Shin-ichi IshikawaMakoto Itoh
Mar 27, 2002·Connective Tissue Research·Joel GautronYves Nys
Apr 12, 2002·Journal of Controlled Release : Official Journal of the Controlled Release Society·A Hatefi, B Amsden
Sep 6, 2002·The Journal of Cell Biology·R C Liddington, M H Ginsberg
Dec 6, 2002·The American Journal of Pathology·Susan A SteitzCecilia M Giachelli
Dec 28, 2002·Journal of Agricultural and Food Chemistry·Yoshinori MineZeina Kassaify
Apr 23, 2003·Poultry Science·T NakanoL Ozimek
Jun 12, 2003·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·W R WalshR M Gillies
Aug 19, 2003·Biomaterials·Ulrich HerselHorst Kessler
Aug 20, 2003·Journal of Biomedical Materials Research. Part a·L HuangS M Kumta
Feb 27, 2004·Journal of Biomedical Materials Research. Part a·C T Harris, L F Cooper
Apr 23, 2004·Trends in Cell Biology·Nathalie OrtegaZena Werb
Jul 14, 2004·Biochemical and Biophysical Research Communications·Daiki TsukamotoKazuyoshi Endo
Sep 15, 2004·Journal of Structural Biology·M S FernandezJ L Arias
May 18, 2005·Bioresource Technology·W T TsaiC W Yeh
Aug 3, 2005·Matrix Biology : Journal of the International Society for Matrix Biology·Yong Mao, Jean E Schwarzbauer
Oct 11, 2005·Annual Review of Cell and Developmental Biology·M A ArnaoutJ-P Xiong
Dec 21, 2005·Journal of Biomaterials Applications·Muzaffer AslanErtunç Dayi
Apr 15, 2006·Marine Biotechnology·Cen Zhang, Rongqing Zhang
Apr 22, 2006·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Masato YanoHiroshi Miyamoto
Apr 26, 2006·Bioscience, Biotechnology, and Biochemistry·Tamao InoKoji Takahashi
Nov 11, 2006·Journal of Biomaterials Science. Polymer Edition·Feng YiJian Yu
Dec 8, 2006·Proteomics·Karlheinz MannMatthias Mann
May 8, 2007·Journal of Materials Science. Materials in Medicine·D Siva Rama KrishnaT S Sampath Kumar
Aug 2, 2007·Biomacromolecules·Kiyotaka Shiba, Tamiko Minamisawa
Aug 19, 2007·Current Opinion in Clinical Nutrition and Metabolic Care·Ken Smith, Michael J Rennie
Aug 28, 2007·Proteomics·Karlheinz Mann
Sep 28, 2007·Wilderness & Environmental Medicine·Yehuda Zadik
Oct 18, 2007·Biopolymers·Julie Glowacki, Shuichi Mizuno
Mar 28, 2008·Bioinspiration & Biomimetics·Geun Hyung KimWan Doo Kim
May 3, 2008·Proteomics·Karlheinz Mann
May 7, 2008·Biomedical Materials·GeunHyung KimYoung Ho Koh
May 22, 2008·Journal of Tissue Engineering and Regenerative Medicine·J I AriasJ L Arias
Jun 24, 2008·Journal of Proteome Research·Chiara D'AmbrosioPier Giorgio Righetti
Oct 9, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Andrónico Neira-CarrilloJosé L Arias
Nov 6, 2008·Annual Review of Genetics·Nils Kröger, Nicole Poulsen
Dec 3, 2008·Journal of Biomedical Materials Research. Part a·Jian-Wei LuJian Yu
Dec 17, 2008·Journal of Chromatography. a·Alessia FarinazzoPier Giorgio Righetti
May 20, 2009·Cellular and Molecular Life Sciences : CMLS·Megan L H Rose, Maxwell T Hincke
May 26, 2009·International Journal of Pharmaceutics·Yunying TaoJun Pan
Sep 29, 2009·Colloids and Surfaces. B, Biointerfaces·Thomas JensenFlemming Besenbacher
Nov 4, 2009·Cell and Tissue Research·Kwok Yeung TsangKathryn S E Cheah
Mar 17, 2010·Acta Biomaterialia·Fernando G TorresAlfredo Hijar
Nov 3, 2010·Colloids and Surfaces. B, Biointerfaces·Ying ZhangJiangfeng Song
Sep 29, 2011·Biopolymers·Nicholas N AshtonRussell J Stewart
Dec 29, 2011·Frontiers in Bioscience (Landmark Edition)·Maxwell T HinckeMarc D McKee
Jun 29, 2012·Journal of Tissue Engineering and Regenerative Medicine·L A StrobelU Kneser
Jan 23, 2013·Journal of Mammary Gland Biology and Neoplasia·Celia ByrneMary Beth Martin
Jul 23, 2013·Food Chemistry·Shuchen HsiehFeng-Huei Lin
Jan 25, 2014·Advances in Colloid and Interface Science·Partha Sarathi Guru, Sukalyan Dash
Sep 12, 2014·Biotechnology Journal·Yun Jung YangHyung Joon Cha
Mar 1, 2013·Materials Science & Engineering. C, Materials for Biological Applications·S F D'SouzaB S Kubal
Feb 6, 2015·Journal of Clinical and Diagnostic Research : JCDR·George Sam, Baiju Radhamoni Madhavan Pillai
May 23, 2015·Open Biology·David Anthony Slatter, Richard William Farndale


Jan 3, 2019·Chemistry : a European Journal·Ludmila KrejčováMartin Pumera
Nov 2, 2019·Journal of Biological Engineering·Leila MohammadzadehMehrdad Mahkam
May 23, 2020·Polymers·Ionela Andreea NeacsuFlorin Iordache
Mar 26, 2021·Journal of Biomedical Materials Research. Part a·Armin AmirsadeghiSeyeddeh-Sara Hashemi

Related Concepts

Chorion proteins
Egg White Proteins
Egg Shell
Extracellular Matrix
Membranes, Artificial
Tissue Engineering
Regenerative Medicine

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.


Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Bacterial Cell Wall Structure (ASM)

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.

Bacterial Cell Wall Structure

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here

Adult Stem Cells

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.

Calcium & Bioenergetics

Bioenergetic processes, including cellular respiration and photosynthesis, concern the transformation of energy by cells. Here is the latest research on the role of calcium in bioenergetics.

Related Papers

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
Yu ZhaoShuling Bai
Experimental Eye Research
Jacqueline ReinhardAndreas Faissner
© 2021 Meta ULC. All rights reserved