PMID: 8586774Jun 1, 1995Paper

Soluble fiber enhances the hypocholesterolemic effect of the step I diet in childhood

Journal of the American College of Nutrition
C L WilliamsD Puder

Abstract

Psyllium, a water-soluble fiber, has been shown to have a cholesterol-lowering effect in studies of adults. A small number of studies in children have produced variable results. A 12-week, randomized, single-blind, placebo-controlled, parallel clinical trial was conducted to test the effectiveness of psyllium in lowering total (TC) and low-density lipoprotein cholesterol (LDL-C) in 50 healthy 2 to 11 year old children. Children with two baseline LDL-C levels > or = 110 mg/dL were invited to participate in the trial, and were randomly assigned to follow a usual Step I (Control) diet of low dietary fat, saturated fat and cholesterol, or a Step I diet enriched with psyllium. Children consumed two 1-oz boxes of cereal per day, with each box of psyllium-enriched cereal containing 3.2 g of soluble fiber, and each box of placebo cereal containing less than 0.5 g of soluble fiber. Greater reduction of total and LDL-cholesterol, and increase in HDL-cholesterol were noted after 12 weeks of the psyllium-enriched Step I diet compared to the Step I control diet. Total cholesterol decreased 21 mg/dL for the high fiber group compared with 11.5 mg/dL for the control group. LDL-C decreased 23 mg/dL for the high fiber group compared with 8.5 mg/...Continue Reading

References

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Citations

Jun 16, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Francesco MartinoTarcisio Niglio
Dec 29, 1999·Journal of the American College of Nutrition·C L WilliamsL Campanaro
Oct 1, 1995·Journal of the American Dietetic Association·C L Williams
Jan 22, 2008·Public Health·P D B CampagnoloA T Stein
Aug 2, 2001·Journal of the American Dietetic Association·S M ColeD L Cockerham
Apr 2, 2009·Nutrition Reviews·James W AndersonChristine L Williams
Jul 30, 1999·The American Journal of Clinical Nutrition·R NicolosiG L Blackburn

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