Soluble fragment of HER2/neu receptor in the serum of patients with breast cancer with different levels of this protein expression in the tumor

Bulletin of Experimental Biology and Medicine
N E KushlinskiiV P Letyagin

Abstract

Serum level of soluble HER2/neu in patients with tumors characterized by high expression of this protein (2+/3+ according to immunohistochemical analysis) was significantly higher than in patients with low expression of HER2/neu and in women with benign diseases of the mammary glands. The level of HER2/neu in the serum decreased after removal of the primary tumor in the majority of patients.

References

Aug 15, 2000·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A Hamilton, M Piccart
Jul 19, 2002·Clinical Breast Cancer·Raquel Andrade Nunes, Lyndsay N Harris
Jun 18, 2003·Clinical Biochemistry·Diana LüftnerKurt Possinger
Aug 5, 2003·The Oncologist·Jeffrey S RossKenneth J Bloom
Jun 1, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M De LaurentiisS De Placido
Jan 4, 2006·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Sally Murray
Feb 7, 2006·Cancer Letters·Rita Nahta, Francisco J Esteva
Feb 8, 2006·Journal of Clinical Pathology·S-Y KongE S Lee

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Citations

Aug 3, 2010·The Breast : Official Journal of the European Society of Mastology·Mehdi FarzadniaNasrin Moheghi
Dec 23, 2009·Bulletin of Experimental Biology and Medicine·N E KushlinskyM A Digaeva

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