Solvation of acylium fragment ions in electrospray ionization quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry

Journal of Mass Spectrometry : JMS
Z Guan, J M Liesch

Abstract

In electrospray ionization (ESI) quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry, certain fragment ions (e.g. acylium ions) generated either during the ion transportation process (in the source interface region) or in the ion trap are found to undergo ion--molecule reactions with ESI solvent molecules (water, acetonitrile and aliphatic alcohols) to form adduct species. These unexpected solvated fragment ions severely complicate the interpretation of mass spectrometic data. High-resolution accurate mass measurements are important in establishing the elemental compositions of these adduct species and preventing erroneous data interpretation.

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Citations

Dec 25, 2015·Analytical and Bioanalytical Chemistry·Élida AlechagaMaria Teresa Galceran
Sep 20, 2011·Biochimica Et Biophysica Acta·Teresa A GarrettZiqiang Guan
Dec 15, 2015·Rapid Communications in Mass Spectrometry : RCM·Sandra OsburnMichael J Van Stipdonk
May 3, 2008·Journal of Pharmaceutical and Biomedical Analysis·Valeria GiancottiClaudio Baiocchi
Jun 29, 2006·Rapid Communications in Mass Spectrometry : RCM·Athula B AttygalleEinar J Stauber
Sep 21, 2010·Journal of Mass Spectrometry : JMS·Chang-Ching ChanAthula B Attygalle
Mar 10, 2010·Rapid Communications in Mass Spectrometry : RCM·Paulo J Amorim MadeiraM Helena Florêncio
Oct 11, 2012·ACS Medicinal Chemistry Letters·Sheo B SinghJanet C Onishi
Oct 11, 2002·Journal of Mass Spectrometry : JMS·Adrian WeiszAsher Mandelbaum
May 31, 2017·Rapid Communications in Mass Spectrometry : RCM·Dejan NikolićRichard B van Breemen
Jun 8, 2001·Journal of Mass Spectrometry : JMS
Jun 22, 2018·Analytical and Bioanalytical Chemistry·Daniel G Beach, Wojciech Gabryelski
Feb 12, 2011·Physical Chemistry Chemical Physics : PCCP·Jonas WarnekeDetlef Gabel
Jan 1, 2015·Journal of Mass Spectrometry : JMS·Axel TreuThomas Dülcks
Jan 22, 2010·The Journal of Organic Chemistry·Frank DreiockerMathias Schäfer

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