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Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry

Analytical Chemistry

Feb 2, 2006

Elizabeth WantGary Siuzdak

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Abstract

The aim of metabolite profiling is to monitor all metabolites within a biological sample for applications in basic biochemical research as well as pharmacokinetic studies and biomarker discovery. Here, novel data analysis software, XCMS, was used to monitor all metabolite features detec...read more

Mentioned in this Paper

Serum Proteins
Tandem Mass Spectrometry
Centrifugation
Organic solvent product
Mass Spectrometry
Liquid Chromatography Mass Spectrometry
Solvents
Acids
Metabolite
Assay
283
Paper Details
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Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry

Analytical Chemistry

Feb 2, 2006

Elizabeth WantGary Siuzdak

PMID: 16448047

DOI: 10.1021/ac051312t

Abstract

The aim of metabolite profiling is to monitor all metabolites within a biological sample for applications in basic biochemical research as well as pharmacokinetic studies and biomarker discovery. Here, novel data analysis software, XCMS, was used to monitor all metabolite features detec...read more

Mentioned in this Paper

Serum Proteins
Tandem Mass Spectrometry
Centrifugation
Organic solvent product
Mass Spectrometry
Liquid Chromatography Mass Spectrometry
Solvents
Acids
Metabolite
Assay
283

Feeds With Similar Papers

Metabolomics

Metabolomics refers to the large-scale study of profiling all metabolites in biological systems in a non-targeted manner. Here is the latest research.

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