journal cover

Soman-induced convulsions in rats terminated with pharmacological agents after 45 min: neuropathology and cognitive performance

Neurotoxicology

Jan 1, 2005

Trond MyhrerPål Aas

Get paper from

Abstract

It has been demonstrated that a triple regimen consisting of procyclidine (6 mg/kg), diazepam (10 mg/kg) and pentobarbital (30 mg/kg) can effectively terminate soman-induced (1 x LD50) seizures/convulsions in rats when administered 30-40 min following onset. However, convulsive activity...read more

Mentioned in this Paper

Acetylcholine Measurement
NOVA2 gene
Memory Disorders
Cognition
Plexiglas
Specimen Type - Electrode
Olfactory
Diazepam
Neuro-Oncological Ventral Antigen 2
Discrimination (Process of Differentiation)
Paper Details
References
  • References21
  • Citations36
123
  • References21
  • Citations36
1234

Similar Papers Found In These Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Complex Memory Functions

This feed focuses on complex memory functions, including remote memory, recognition memory, and spatial cognition. Here is the latest research.

Basal Forebrain- Circuits

Basal forebrain is a region in the brain important for production of acetylcholine and is the major cholinergic output of the CNS. Discover the latest research on circuits in the basal forebrain here.

Temporal Lobe Epilepsy

Temporal lobe epilepsy (TLE) affects brain areas beyond the temporal lobes due to connections of the hippocampi and other temporal lobe structures. Discover the latest research on TLE here.

Neurocognition and Behaviour

This feed focuses on neurobehavioral manifestations, neurocognitive development, and cognition disorders. Here is the latest research.

Limbic System

The limbic system is comprised of several different parts of the brain involved in emotion, motivation, learning, and memory. Discover the latest research on the limbic system here.

© 2019 Meta ULC. All rights reserved

Soman-induced convulsions in rats terminated with pharmacological agents after 45 min: neuropathology and cognitive performance

Neurotoxicology

Jan 1, 2005

Trond MyhrerPål Aas

PMID: 15527872

DOI: 10.1016/j.neuro.2004.07.011

Abstract

It has been demonstrated that a triple regimen consisting of procyclidine (6 mg/kg), diazepam (10 mg/kg) and pentobarbital (30 mg/kg) can effectively terminate soman-induced (1 x LD50) seizures/convulsions in rats when administered 30-40 min following onset. However, convulsive activity...read more

Mentioned in this Paper

Acetylcholine Measurement
NOVA2 gene
Memory Disorders
Cognition
Plexiglas

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References21
  • Citations36
123
  • References21
  • Citations36
1234

Get paper from

/papers/soman-induced-convulsions-in-rats-terminated-with/15527872