PMID: 1089541Jan 15, 1975

Somatic antigen of Shigella dysenteriae type 3. Structural features of specific polysaccharide chain

European Journal of Biochemistry
B A DmitrievI L Hofman

Abstract

On mild acid hydrolysis of lipolysaccharide from Shigella dysenteriae type 3 the O-specific polysaccharide (hapten) was obtained which appeared to be acidic branched hexosaminoglycan. The repeating unit of this polysaccharide represents a pentasaccharide composed of two D-galactose residues, N-acetyl-D-galactosamine, D-glucose and unidentified acidic component. On the basis of methylation analysis, periodate oxidation, partial acid hydrolysis and chromic anhydride oxidation it is concluded that the structure of the chemical repeating unit of polysaccharide is (see article) where Glcp is glucopyranose, Galp is galactopyranose, Galf is galactofuranose, GalNAcp is 2-acetamido-2-deoxygalactopyranose and where the configuration of galactofuranoside glycosidic linkage and the structure of the acidic monosaccharide A are not known.

References

Oct 1, 1983·Molecular Immunology·S BasuS G Dastidar
May 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·H J JenningsD L Kasper
Feb 16, 1976·European Journal of Biochemistry·W Gromska, H Mayer
Nov 15, 1978·European Journal of Biochemistry·B Kedzierska
Apr 22, 2008·FEMS Microbiology Reviews·Bin LiuLei Wang
Jul 12, 1988·Biochemistry·F MichonH J Jennings

Citations

Jan 3, 1973·European Journal of Biochemistry·B LindbergD A Simmons
Jul 2, 1973·European Journal of Biochemistry·E Romanowska, V Reinhold
Dec 17, 1973·European Journal of Biochemistry·B A DmitrievI L Hofman
Jul 1, 1969·Journal of Biochemistry·S Hase, Y Matsushima
Sep 1, 1953·Journal of Bacteriology·W H EWING

Related Concepts

Anhydrides
Protein Methylation
Chromic
Dysentery, Bacillary
GALP gene
Acetylgalactosamine
Galactose
Oxidation
Polysaccharides, Bacterial
Mass Spectrometry

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