PMID: 6409609Aug 1, 1983Paper

Somatic antigens of Pseudomonas aeruginosa. The structure of O-specific polysaccharide chains of P. aeruginosa O:3(a),c and O:3a,d,e lipopolysaccharides

European Journal of Biochemistry
Knirel YuAG M Mashilova

Abstract

On mild acid degradation of Pseudomonas aeruginosa O:3(a),c, O:3a,d,e and O:3(a),d,f lipopolysaccharides O-specific polysaccharides were isolated. The trisaccharide repeating units of O:3(a),c and O:3a,d,e polysaccharides contained 2-acetamido-2,6-dideoxy-D-galactose and 2,3-(1-acetyl-2-methyl-2-imidazolino-5, 4)-2,3-dideoxy-D-mannuronic acid, which were identified previously as the constituents of P. aeruginosa O:3a,b and O:3a,d O-specific polysaccharides, as well as 2,3-diacetamido-2, 3-dideoxyl-L-guluronic acid, which has never before been found in nature. The last monosaccharide was identified without being isolated in the free state, by means of 13C nuclear magnetic resonance spectroscopy. The structures of O:3(a),c and O:3a,d,e polysaccharides were established by selective hydrogen fluoride solvolysis followed by modification of the trisaccharides obtained and analysis of the 13C nuclear magnetic resonance spectra at each modification stage. The polysaccharides possessed similar structures of repeating units differing from each other in the anomeric configuration of the N-acetylfucosamine residue only: leads to 4)DManImU-(beta 1 leads to 4) LGul(NAc)2U(alpha 1 leads to 3)DFucNAc(beta 1-and leads to 4)DManImU(beta 1 leads ...Continue Reading

References

Oct 1, 1977·Analytical Biochemistry·A J Mort, D T Lamport
Nov 1, 1974·The Journal of Infectious Diseases·J C Sadoff, M S Artenstein
Jan 1, 1949·Acta Pathologica Et Microbiologica Scandinavica·O OUCHTERLONY

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Citations

May 2, 1986·European Journal of Biochemistry·D Oxley, S G Wilkinson
Apr 22, 2008·FEMS Microbiology Reviews·Bin LiuLei Wang
Sep 19, 2006·FEMS Microbiology Letters·Michelle KilcoyneAngela V Savage
Sep 8, 1999·Microbiology and Molecular Biology Reviews : MMBR·H L RocchettaJ S Lam
Jun 1, 1989·Journal of Clinical Microbiology·J GrzybowskiM Kłos

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