Somatic chromosomal abnormalities in infertile men and women

Cytogenetic and Genome Research
U A Mau-Holzmann


Infertility--the inability to achieve conception or sustain a pregnancy through to live birth--is very common and affects about 15% of couples. While chromosomal or genetic abnormalities associated with azoospermia, severe oligozoospermia or primary ovarian failure were of no importance for reproduction prior to the era of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI), advances in assisted reproductive techniques (ART) now enable many infertile couples to have children. These developments have raised the question of the genetic consequences of ICSI: concerns of the potential harm of the invasive procedure and concerns about the genetic risk. The infertile male and female definitely have an increased risk to carry a chromosomal abnormality. Detection of such an abnormality is of fundamental importance for the diagnosis of infertility, the following treatment, the evaluation of the risk for the future child and the appropriate management of the pregnancy to be obtained. Therefore, cytogenetic screening of both partners is mandatory prior to any type of ART. The present review is based on several surveys on male and female infertility and analyzes the types and frequencies of the different reported chrom...Continue Reading


Jan 1, 1992·Cytogenetics and Cell Genetics·A KovácsT H Howard
Aug 1, 1989·Clinical Genetics·L HensI Liebaers
Jan 1, 1989·Urologia Internationalis·T MatsudaO Yoshida
Jan 1, 1988·Cytogenetics and Cell Genetics·B QuackA C Chandley
Jun 1, 1986·American Journal of Medical Genetics·M CampanaG Neri
Dec 1, 1986·Human Genetics·G BourrouillouN Dastugue
Mar 1, 1985·Fertility and Sterility·P P Mahlstedt
Jan 1, 1985·Human Genetics·G BourrouillouP Colombies
Jan 1, 1972·Cytogenetics·A C ChandleyP A Jacobs
Jan 1, 1966·Humangenetik·W Fuhrmann
Jan 1, 1984·Clinical Genetics·M MićićV Diklić
Apr 1, 1982·Clinical Genetics·A D CarothersL Smith
Jun 18, 1994·Lancet·D L HealyA N Andersen
Jul 1, 1993·American Journal of Medical Genetics·A Schinzel
Jan 1, 1993·Cytogenetics and Cell Genetics·H A AnsariG Stranzinger
Jan 1, 1993·Cytogenetics and Cell Genetics·R JohannissonU Löhrs
May 15, 1993·American Journal of Medical Genetics·M TeyssierM Pugeat
Apr 1, 1993·Human Reproduction·R LangeW Engel
Nov 1, 1995·Human Genetics·K Madan
Oct 21, 1995·The Veterinary Record·B PrakashR K Malik
May 1, 1996·Human Reproduction·R H Martin
May 1, 1996·Human Reproduction·A C Chandley, T B Hargreave
Jan 1, 1995·Reproduction, Fertility, and Development·P H VogtM R Köhler
Dec 1, 1996·Human Reproduction·N Pandiyan, A M Jequier

❮ Previous
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Apr 14, 2011·Human Reproduction Update·F PellestorP Sarda
Jun 26, 2012·Current Opinion in Obstetrics & Gynecology·Peter J Stahl, Peter N Schlegel
Apr 9, 2008·Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation·E MarchinaS Barlati
Dec 25, 2008·Molecular Cytogenetics·Serdar KasakyanMoncef Benkhalifa
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Nov 19, 2011·Systems Biology in Reproductive Medicine·Ester AntonJoan Blanco
Nov 30, 2013·The Urologic Clinics of North America·James M Hotaling
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Apr 22, 2008·The Urologic Clinics of North America·Robert D Oates
Nov 29, 2007·International Journal of Andrology·A TzschachD Steinberger
Jan 24, 2007·International Journal of Andrology·A K FaureS Rousseaux
Mar 9, 2011·Annals of the New York Academy of Sciences·Kathleen HwangDolores J Lamb
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Jan 22, 2010·The Journal of Clinical Endocrinology and Metabolism·Robert I McLachlan, Moira K O'Bryan
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