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Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Nature

Oct 1, 2019

Simon F BrunnerPeter J. Campbell

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Abstract

The most common causes of chronic liver disease are excess alcohol intake, viral hepatitis and non-alcoholic fatty liver disease, with the clinical spectrum ranging in severity from hepatic inflammation to cirrhosis, liver failure or hepatocellular carcinoma (HCC). The genome of HCC exh...read more

Mentioned in this Paper

Malignant Neoplasms
Clone Cells
DNA Mutational Analysis
Fibrosis
Genome
Inflammation
Liver
Liver Cirrhosis
Neoplasms, Multiple Primary
Phylogeny
205
6
2
78
1
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Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Nature

Oct 1, 2019

Simon F BrunnerPeter J. Campbell

PMID: 31645727

DOI: 10.1038/s41586-019-1670-9

Abstract

The most common causes of chronic liver disease are excess alcohol intake, viral hepatitis and non-alcoholic fatty liver disease, with the clinical spectrum ranging in severity from hepatic inflammation to cirrhosis, liver failure or hepatocellular carcinoma (HCC). The genome of HCC exh...read more

Mentioned in this Paper

Malignant Neoplasms
Clone Cells
DNA Mutational Analysis
Fibrosis
Genome
205
6
2
78
1

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