PMID: 8594564Jan 1, 1996Paper

Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

Nucleic Acids Research
M HollsteinC C Harris

Abstract

In 1994 we described a list of approximately 2500 point mutations in the p53 gene of human tumors and cell lines which we had compiled from the published literature and made available electronically through the file server at the EMBL Data Library. This database, updated twice a year, now contains records on 4496 published mutations (July 1995 release) and can be obtained from the EMBL Outstation-the European Bioinformatics Institute (EBI) through the network or on CD-ROM. This report describes the criteria for inclusion of data in this database, a description of the current format and a brief discussion of the current relevance of p53 mutation analysis to clinical and biological questions.

References

Nov 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·S Kunala, D E Brash
Sep 4, 1990·Biochemistry·T A Kunkel
Jul 5, 1991·Science·M HollsteinC C Harris
Nov 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·D E BrashJ Pontén
Mar 11, 1994·Science·S Tornaletti, G P Pfeifer
Apr 1, 1994·International Journal of Cancer. Journal International Du Cancer·T SoussiB Schlichtholz
Jun 1, 1994·International Journal of Cancer. Journal International Du Cancer·D P Lane
Jan 1, 1993·Annual Review of Biochemistry·A J Levine
Oct 28, 1993·The New England Journal of Medicine·C C Harris, M Hollstein
Feb 1, 1993·Computer Applications in the Biosciences : CABIOS·T Etzold, P Argos

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Citations

Jun 21, 1996·International Journal of Cancer. Journal International Du Cancer·R MontesanoP Hainaut
Aug 22, 1996·International Journal of Cancer. Journal International Du Cancer·P WürlF W Rath
Mar 28, 1997·International Journal of Cancer. Journal International Du Cancer·C BarnasP Hainaut
May 15, 1998·Journal of Cellular Biochemistry·K WillW Deppert
Sep 27, 2000·International Journal of Cancer. Journal International Du Cancer·D TongR Zeillinger
Oct 24, 2001·Electrophoresis·R KaczanowskiK Kucharczyk
Aug 14, 1999·Arthritis and Rheumatism·F KullmannU Müller-Ladner
Aug 1, 1996·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·M B Kastan
Feb 6, 1998·Human Mutation·J W LucaM F Hansen
Sep 5, 2002·International Journal of Cancer. Journal International Du Cancer·George XinarianosJohn K Field
May 11, 2006·International Archives of Occupational and Environmental Health·A Pilger, H W Rüdiger
Oct 10, 2007·Development Genes and Evolution·Aurora M Nedelcu, Christopher Tan
Jun 7, 2013·Aging Clinical and Experimental Research·Jolanta Dorszewska
Aug 17, 2004·International Journal of Oral and Maxillofacial Surgery·K OhkiK Ooya
May 5, 2004·Respiratory Physiology & Neurobiology·Jolanta Dorszewska, Zofia Adamczewska-Goncerzewicz
Nov 12, 1998·The American Journal of Pathology·C ZietzU Löhrs
Jun 26, 1999·Clinical Biochemistry·J PooartV Lulitanond
Sep 28, 1998·Mutation Research·M HollsteinJ Brickmann
Jul 30, 2003·Cancer Genetics and Cytogenetics·Avery A Sandberg, Julia A Bridge
Jan 1, 1997·Trends in Genetics : TIG·A HartmannS S Sommer
Dec 3, 2002·Archives of Medical Research·Ma del Carmen MejíaAntonio Llombart-Bosch
Sep 10, 2003·Cancer Letters·Kin-Tak ChanMaria Li Lung
Feb 3, 1999·Cancer Letters·M L LungR D Iggo
Aug 24, 1999·Cancer Letters·W ThangniponK Hayashi
Dec 12, 2001·Mutation Research·S B Waters, S A Akman
Dec 22, 1999·Mutation Research·L MengM Nadji
Jan 1, 1997·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·K Angelopoulou, E P Diamandis
Oct 3, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C TolisG Giaccone
Mar 20, 1999·Genetic Analysis : Biomolecular Engineering·J H GraberC R Cantor
Mar 29, 2000·The International Journal of Biochemistry & Cell Biology·S M ColleyS P Klinken

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