PMID: 9416924Jan 7, 1998Paper

Somatodendritic and axonal anatomy of intracellularly labeled serotonergic neurons in the rat medulla

The Journal of Comparative Neurology
K Gao, P Mason

Abstract

A knowledge of the anatomy of medullary serotonergic cells is critical to understanding local and brainstem circuits in which these cells participate. Serotonergic neurons (n = 16) were identified, as previously described (Mason [1997] J. Neurophysiol. 77:1087-1098) by their slow and steady background discharge in halothane anesthetized rats. Neurons were then intracellularly labeled with Neurobiotin and visualized with 3,3'diaminobenzidine. The validity of the physiological identification of serotonergic cells was confirmed by processing two neurons that were physiologically characterized as serotonergic for serotonin immunoreactivity; both tested cells contained immunoreactive serotonin. The dendrites and axon of each labeled cell were reconstructed by using a three-dimensional computerized system. Somata were small or medium in size and had fusiform, triangular, or multipolar shapes. The dendritic arbor was constricted with most dendrites extending for less than 500 microm from the soma. All labeled axons projected caudally and travelled in the ventrolateral medulla, either dorsal or ventral to the lateral reticular nucleus. Most cells had collaterals and/or dense axonal swellings in the nucleus reticularis gigantocellularis...Continue Reading

References

Nov 1, 1992·Pflügers Archiv : European journal of physiology·W H Wang, T A Lovick
Nov 1, 1990·The Journal of Comparative Neurology·P MasonH L Fields
Jul 15, 1991·The Journal of Comparative Neurology·E J Van BockstaeleM T Shipley
Nov 8, 1987·The Journal of Comparative Neurology·K B Thor, C J Helke
Oct 8, 1989·The Journal of Comparative Neurology·P Mason, H L Fields
Oct 1, 1989·Journal of the Autonomic Nervous System·T A Lovick
Aug 15, 1986·The Journal of Comparative Neurology·A I BasbaumH J Ralston
Oct 29, 1984·Brain Research·H VanegasH L Fields
Jul 1, 1983·Experimental Neurology·F P ZemlanD W Pfaff
Nov 1, 1993·The Journal of Comparative Neurology·S B Potrebic, P Mason
Aug 15, 1993·The Journal of Comparative Neurology·S Manaker, L J Tischler

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Citations

Aug 24, 2007·Journal of Neurophysiology·Peggy MasonJonathan R Genzen
Aug 28, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Kevin M HellmanPeggy Mason
Oct 12, 2001·The Journal of Comparative Neurology·K Gao, P Mason
Feb 20, 2004·Journal of Neurophysiology·Malcolm W Nason, Peggy Mason
Aug 4, 2010·Neuroscience and Behavioral Physiology·A N InyushkinE M Inyushkina
Mar 4, 2003·Journal of Neurophysiology·Thaddeus S Brink, Peggy Mason
Sep 8, 2007·Journal of Applied Physiology·Mirela B DiasLuiz G S Branco
Aug 10, 2019·Journal of Neuropathology and Experimental Neurology·Hannah C Kinney, Robin L Haynes

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