PMID: 6989150Jan 1, 1980Paper

Somatomedin activity and growth hormone secretion. I. Changes related to body weight in anorexia nervosa

Acta paediatrica Scandinavica
R RappaportP Czernichow

Abstract

Anorexia nervosa in childhood and adolescence, associated with impaired growth can be considered as a form of chronic malnutrition. Twelve patients aged 11 to 17 years were investigated. In spite of increased GH secretion, plasma somatomedin activities were diminished in 8 cases. Plasma T4, T3 and arginine stimulated insulin secretion were also decreased. In six patients who gained weight a significant negative correlation was found between weight deficit and plasma somatomedin activity. Prolonged administration of growth hormone in one case did not stimulate the generation of somatomedin activity. Nutrition and increased insulin secretion could plan a role in changes observed during recovery.

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Citations

May 1, 1991·Acta paediatrica Scandinavica·M WallensteenG Dahlquist
Jun 8, 2001·Journal of Pediatric Endocrinology & Metabolism : JPEM·R K StøvingC Hagen
Dec 11, 2002·The International Journal of Eating Disorders·Victor W SwayzeSteve Ziebell
May 7, 2005·International Journal of Clinical Practice. Supplement·M ShariffK Meeran
Nov 1, 1987·European Journal of Pediatrics·M HermanussenW G Sippell
Apr 26, 2008·Endocrine Reviews·Andrea GiustinaErnesto Canalis
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Mar 1, 1997·The American Journal of Sports Medicine·P PigeonP Rochiccioli
Feb 1, 2003·Nutrition in Clinical Care : an Official Publication of Tufts University·Madhusmita Misra, A Klibanski
Dec 22, 1999·The Journal of Clinical Endocrinology and Metabolism·L A SoykaA Klibanski
Jul 1, 1986·Acta paediatrica Scandinavica·M HermanussenW G Sippell
Aug 1, 1993·Journal of the American College of Nutrition·K K HillC J McClain

Related Concepts

Anorexia Nervosa
Novolin
Somatomedins
Recombinant Growth Hormone
Novothyral
Cytomel

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Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.