Somatosensory evoked potentials in rats with hypocalcemia

Japanese Journal of Medicine
F KandaT Fujita

Abstract

The effects of hypocalcemia on somatosensory evoked potentials (SEPs) were studied in rats. The SEP in awake rats consisted of an unstable, large, negative wave (Nmax) preceded by a small positive one (P1). The P1 appeared to be a subcortical potential and Nmax appeared to represent the function of the cerebral cortex. With the decrease in calcium concentration caused by parathyroidectomy, as well as by administration of EDTA, an augmentation of amplitudes of the Nmax and a reduction in the SEP recovery functions were observed. The latency of P1 was hardly changed. The decrease in the SEP recovery functions possibly reflects a reduction in synaptic efficiency, and the increasing amplitude of the SEP probably reflects the cortical hyperexcitability caused by hypocalcemia.

Citations

Apr 15, 2003·The Journal of Physiology·Andrea BurgoCristina Fasolato

❮ Previous
Next ❯

Related Concepts

Related Feeds

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.

Related Papers

International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology
Francesco TaddeiL Mecacci
Journal of the Neurological Sciences
M YamamotoA Igata
Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Domenico RestucciaGiacomo Della Marca
© 2022 Meta ULC. All rights reserved