Somatosensory perception in a remote pain-free area and function of diffuse noxious inhibitory controls (DNIC) in patients suffering from long-term trapezius myalgia

European Journal of Pain : EJP
Ann-Sofie LefflerEva Kosek

Abstract

In patients with localized musculoskeletal pain, spread of pain and tenderness outside the primarily painful area and sometimes even generalization of pain have been reported, the latter possibly indicating a dysfunction of endogenous pain modulatory systems. The purpose of the study was to use patients with long-term trapezius myalgia as a model to investigate the possible influence of a localized muscle pain on somatosensory processing in a remote pain-free area and the effect of heterotopic noxious conditioning stimulation (HNCS) on 'diffuse noxious inhibitory controls' (DNIC) related mechanisms. Altered somatosensory processing may indicate subclinical derangement of endogenous modulatory systems. Ten patients with long-term (> or = 1 year) trapezius myalgia and 10 age- and sex-matched healthy controls participated. Pressure pain sensitivity, low threshold mechanoreceptive function and thermal sensitivity, including thermal pain, were assessed at the right thigh before, during and following HNCS. Pain was induced in the forearm by the tourniquet test. At rest allodynia to pressure was found at the thigh in conjunction with hypoaesthesia to cold (p<0.03 and p<0.01 respectively), in patients compared with controls. During HNC...Continue Reading

Associated Clinical Trials

May 30, 2018·Jonathan Daniel Telles

References

Jun 1, 1990·Acta Neurologica Scandinavica·D ClausB Neundörfer
Oct 1, 1990·Acta Orthopaedica Scandinavica·S E LarssonP A Oberg
Aug 1, 1990·Brain : a Journal of Neurology·T De BrouckerD Le Bars
Feb 19, 1985·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·H L Fields, M M Heinricher
Aug 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·P HanssonP Marchettini
Sep 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·A Ekblom, P Hansson
Jan 1, 1987·The Journal of Hand Surgery·J Bell-Krotoski, E Tomancik
Sep 21, 1974·British Medical Journal·S L O'Driscoll, M I Jayson
Mar 1, 1970·Journal of Neurophysiology·B N Christensen, E R Perl
Dec 1, 1984·Physiology & Behavior·A PertovaaraG Johansson
Dec 20, 1994·Journal of the Neurological Sciences·D Meh, M Denislic
Jul 5, 1994·Proceedings of the National Academy of Sciences of the United States of America·B R DworkinC H Brunia
Feb 20, 1999·Zeitschrift für Rheumatologie·S Mense
Jun 1, 1962·Perceptual and Motor Skills·S WEINSTEIN

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Citations

Sep 9, 2011·Zeitschrift für Rheumatologie·M Späth
Nov 8, 2006·Current Pain and Headache Reports·Richard E Harris, Daniel J Clauw
Jul 20, 2002·Current Rheumatology Reports·Thomas Graven-Nielsen, Lars Arendt-Nielsen
Nov 3, 2010·The Journal of Clinical Investigation·Michael H OssipovFrank Porreca
Jan 1, 2012·Scientifica·Michael H Ossipov
Jun 6, 2014·Experimental Brain Research·Yuka OonoLars Arendt-Nielsen
Aug 1, 2012·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Helen SlaterStephan A Schug
Dec 3, 2013·The Journal of Pain : Official Journal of the American Pain Society·Linda LeRescheMichael Von Korff
Sep 18, 2012·The Journal of Pain : Official Journal of the American Pain Society·Gwyn N LewisPeter J McNair
Jan 16, 2010·The Journal of Pain : Official Journal of the American Pain Society·Gerrit van Wijk, Dieuwke S Veldhuijzen
Jan 9, 2010·The American Journal of Medicine·Daniel J Clauw
Apr 22, 2009·The Journal of Pain : Official Journal of the American Pain Society·Lars Arendt-Nielsen, David Yarnitsky
Jul 2, 2004·Obstetrics and Gynecology·Jutta GieseckeRichard H Gracely
May 17, 2008·The Journal of Pain : Official Journal of the American Pain Society·Claudia M CampbellRoger B Fillingim
Aug 13, 2015·Best Practice & Research. Clinical Rheumatology·Daniel J Clauw
Sep 6, 2005·European Journal of Pain : EJP·Helge KaschTroels Staehelin Jensen
Feb 12, 2004·Arthritis and Rheumatism·Thorsten GieseckeDaniel J Clauw
Oct 10, 2012·Arthritis and Rheumatism·Kristine Phillips, Daniel J Clauw
Jun 19, 2015·The Journal of Pain : Official Journal of the American Pain Society·Matthew C MorrisUma Rao
Dec 15, 2010·Pain·Richard E LiebanoKathleen A Sluka
Jul 30, 2009·The Journal of Pain : Official Journal of the American Pain Society·David A Williams, Daniel J Clauw
Apr 18, 2013·Journal of Acupuncture and Meridian Studies·Michele Gallamini
Dec 3, 2014·The Journal of Pain : Official Journal of the American Pain Society·David M KlynePaul W Hodges
Oct 6, 2005·Pain·Anke PielstickerStefan Lautenbacher
Sep 4, 2013·Pain·Christian GeberFrank Birklein
Oct 1, 2013·Pain·Henrik Bjarke VaegterThomas Graven-Nielsen
Jun 7, 2016·European Journal of Pain : EJP·H B VaegterT Graven-Nielsen
Apr 5, 2018·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Ali AlsouhibaniMarie Hoeger Bement

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