Sep 1, 1976

Some aspects of foetal and uteroplacental metabolism in cows with indwelling umbilical and uterine vascular catheters

The Journal of Physiology
R S Comline, M Silver

Abstract

1. The experiments were carried out on conscious pregnant Jersey cows with intravascular catheters implanted during late gestation in umbilical and uterine vessels. All but three of fifteen animals delivered live healthy calves. 2. Rountine daily analyses were made of blood gas tensions, pH and packed cell volume in foetal and maternal blood; plasma concentrations of glucose, fructose, lactate and urea were also determined. Measurements of plasma free fatty acids and blood acetate concentrations were made less frequently. Foetal heart rate and arterial blood pressure were recorded in animals with an umbilical arterial catheter. 3. The concentration differences between foetal and maternal blood or plasma in glucose, urea and acetate were measured in fifteen animals. The maternal-to-foetal glucose and acetate gradients across the placenta were high while the foetal-to-maternal plasma urea differences were small. 4. In those animals with patent arterial and venous catheters, uterine and umbilical blood flows were measured together with the arteriovenous differences in 02, glucose, acetate and lactate so that rates of foetal and uterine consumption could be estimated. The rates of utilization of O2, glucose and acetate by the foetu...Continue Reading

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Mentioned in this Paper

Metabolic Process, Cellular
Structure of Calf of Leg
Fetal Structures
Entire Fetus
Catheterization
Venous Blood Substance
Lactate
Fructose
Umbilicus (Anatomy)
Vascular Catheters

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