Aug 1, 1978

Some effects of a thallium salt on the proliferation of hair follicle cells

The Journal of Pathology
J B Cavanagh, M Gregson

Abstract

Thallium sulphate has been given to young rats at 4 and 7 days of age and the mitotic activity of the hair follicles has been assessed quantitatively. It has been found that there is a marked decline in mitotic rate over 48 hr in the thallium-treated animals, which is followed by variable amounts of cell death in the matrix zone. No specific mitotic lesion was found or change in cell cycle indices. A failure of energy metabolism is suggested as a possible cause of the inhibition of hair follicle mitosis by thallium.

  • References4
  • Citations4

Citations

Mentioned in this Paper

Entire Hair Follicle
Depression, Chemical
Bulla
Energy Metabolism
Downy Hair
Thallium
Thallium sulfate
Cell Cycle
Metabolic Inhibition
Cell Survival

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