PMID: 2123155Nov 1, 1990Paper

Some genetic aspects of idiopathic and symptomatic absence seizures: waking and sleep EEGs in siblings

Epilepsia
R DegenC Roth

Abstract

Epileptic activity was recorded in the waking and sleep EEG of 62.5% of 80 siblings of 38 patients with absence seizures. Epileptic discharges were noted in waking only in 8.7%, in waking as well as sleep in 28.8%, and in sleep only in 25%. Generalized, partly irregular, and slow spike-wave complexes were found, twice with lateral emphasis. Spike-wave complexes were recorded in 72% of 50 siblings of patients with idiopathic absence and in 46.7% of 30 siblings of patients with symptomatic absence. One epileptic discharge was observed every 108.6 s on the average, without striking differences between siblings of patients with idiopathic (99.7 s) and symptomatic absence (119.3 s). Without any differences between siblings of children with idiopathic and symptomatic absence, the most epileptic discharges were activated in sleep stages C and D, followed by stages A and B. The highest activation rate was observed in the 7-14-year-old group (73.5%) and to a somewhat lesser degree in the group between 15 and 20 years of age (66.7%); fewer epileptic discharges were recorded in younger (25%) and older patients (28.6%). The higher activation rates in the male sex were significant only in siblings of patients with idiopathic absence. Althou...Continue Reading

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Citations

Sep 7, 2002·Mental Retardation and Developmental Disabilities Research Reviews·Linda D Cowan
Apr 1, 1997·Journal of Neurology·A AutretB de Toffol
Apr 3, 2001·Neurophysiologie clinique = Clinical neurophysiology·R Peraita-AdradosJ J García-Peñas
Mar 5, 2008·European Journal of Pediatrics·Jacqueline NuysinkPaul J M Helders
Jan 7, 2004·Epilepsia·Paulo R M de Bittencourt
Jan 17, 2002·Seizure : the Journal of the British Epilepsy Association·S StodieckK van Rijckevorsel
Oct 11, 2014·PloS One·Fahmida A ChowdhuryMark P Richardson
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Jan 1, 1993·Epilepsia·G L Holmes
Mar 29, 2002·Journal of Child Neurology·L James Willmore, Yuto Ueda
Sep 27, 2020·Seizure : the Journal of the British Epilepsy Association·Chaturbhuj RathorePrayag Makwana
Nov 28, 2021·Nature Reviews. Neurology·Bernd J VorderwülbeckeMartin Holtkamp

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Absence Epilepsy

Absence epilepsy is a common seizure disorder in children which can produce chronic psychosocial sequelae. Discover the latest research on absence epilepsies here.