PMID: 1202366Nov 21, 1975Paper

Some physiological and pharmalogical characteristics of the stimulus induced release of norepinephrine from the rabbit superior cervical ganglion

Naunyn-Schmiedeberg's Archives of Pharmacology
J P Noon, R H Roth

Abstract

The cervical sympathetic nerve stimulated release of norepinephrine (NE) from the rabbit superior cervical ganglion (SCG) was characterized. The quantity of NE released per impulse declined with increasing stimulation frequency over the range of 3/sec to 15/sec. Nerve stimulated NE release was potentiated by 1 micromolar desmethylimipramine and 25 micromolar phenoxylbenzamine and inhibited by 1 micromolar bretylium, 25 micromolar methoxamine and 1 micromolar prostaglandin E1. These results suggest that nerve stimulated NE release in the rabbit SCG occurs from sympathetic fibers which are subject to the same neurosecretory control mechanisms as sympathetic fibers elsewhere in the autonomic nervous system.

References

Nov 21, 1975·Naunyn-Schmiedeberg's Archives of Pharmacology·J P NoonR H Roth
Apr 30, 1971·Annals of the New York Academy of Sciences·P Hedqvist
Apr 1, 1972·British Journal of Pharmacology·M A EneroF J Stefano
Nov 1, 1970·The Journal of Pharmacy and Pharmacology·L O Farnebo, B Hamberger
Jan 1, 1971·Acta Physiologica Scandinavica. Supplementum·L O Farnebo, T Malamfors
Dec 1, 1972·European Journal of Pharmacology·S A VogelI J Kopin
Sep 1, 1971·British Journal of Pharmacology·L O Farnebo, B Hamberger
Oct 30, 1970·Annals of the New York Academy of Sciences·J S Goodman, M G Koenig
Sep 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·D G JohnsonI J Kopin
May 1, 1970·Biochemical Pharmacology·F H Leitz, F J Stefano
Aug 29, 1958·The Journal of Physiology·G L BROWNJ S GILLESPIE
Dec 1, 1959·British Journal of Pharmacology and Chemotherapy·A L BOURA, A F GREEN
Mar 1, 1962·Circulation Research·J P GILMORE, J H SIEGEL
Feb 1, 1962·British Journal of Pharmacology and Chemotherapy·G HERTTINGR W PATRICK

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Citations

Jun 5, 1986·European Journal of Pharmacology·D M Araujo, B Collier
Jul 1, 1982·Journal of the Autonomic Nervous System·I A BulyginV M Reprintseva
Oct 1, 1976·General Pharmacology·K Starke, T Endo
Jan 1, 1979·Comparative Biochemistry and Physiology. C: Comparative Pharmacology·L P Jager, J A Schievers
Apr 1, 1980·Journal of Psychedelic Drugs·A Novak

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