PMID: 9052Jan 1, 1976

Some properties of togavirus hemagglutinin studied with the aid of kaolin-adsorbed virus

Archives of Virology
Y Akov


Acidification (at pH 5.75) of Semliki Forest virus and West Nile virus suspensions completely eliminated their hemagglutinating activity within several minutes, but did not affect their infectivity or change their ability to absorb homologous hemagglutination-inhibition antibodies. In order to assay antibody absorption it was necessary to remove all of the immune complex from the reaction mixture, because the immune complex inhibited additional hemagglutinin. Removal of the immune complex can be accomplished by the use of kaolin-absorbed virus. This procedure is simple and dependable and has been carried out with viruses from several groups--Toga-, Myxo-, Paramyxo- and Picornaviridae.


Nov 1, 1973·Journal of Virology·J M DalrympleP K Russell
Dec 1, 1970·The Journal of General Virology·G AppleyardJ L Stanley
Sep 1, 1958·The American Journal of Tropical Medicine and Hygiene·D H CLARKE, J CASALS
Jun 1, 1961·Virology·V RILEY, R CRAMER
Jun 1, 1960·Annals of Tropical Medicine and Parasitology·J H HALE, K PILLAI


Jan 1, 1983·Avian Pathology : Journal of the W.V.P.A·J K Cook

Related Concepts

Antibodies, Viral
Immune complex
Hemagglutination, Viral
Hemagglutinins, Viral
Hydrogen-Ion Concentration
Semliki forest virus
Kunjin virus

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