Some recent developments in the preparation of novel recognition systems: a recognition site for the selective catalysis of an aldol condensation using molecular imprinting and specific affinity motifs for alpha-chymotrypsin using a phage display peptide library

Journal of Molecular Recognition : JMR
Ian A NichollsK Mosbach

Abstract

Molecular imprinting and phage display library technologies are rapidly being accepted as useful techniques for the generation of ligand-selective recognition motifs. The use of molecular imprinting to produce a novel type II aldolase mimic selective for the cobalt(II)-mediated aldol condensation of benzophenone and acetaldehyde is reported here. Furthermore, peptide motifs have been identified which are acting as 'affinity ligands' selective for the recognition of the enzyme alpha-chymotrypsin using phage display techniques.

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Citations

Oct 4, 2014·Chemistry : a European Journal·Emil LindbäckKenneth Wärnmark
Sep 14, 2007·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Francesco PuociFranco Alhaiqu
Jul 9, 2010·The Journal of Pharmacy and Pharmacology·Giuseppe CirilloNevio Picci
Sep 22, 2011·Expert Opinion on Drug Delivery·Francesco PuociNevio Picci
May 1, 2008·Drug Delivery·Francesco PuociNevio Picci
Jul 8, 2008·Chemistry : a European Journal·Davide CarboniMarina Resmini
Nov 20, 2009·Pharmaceutical Development and Technology·Giuseppe CirilloNevio Picci
Jan 10, 2002·Chemical Reviews·Günter Wulff

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