PMID: 3760863Sep 1, 1986Paper

Some transition metal chelates of 8-hydroxyquinoline-5-sulfonamides as possible drugs

Journal of Inorganic Biochemistry
S A IbrahimA M Moharram

Abstract

Fe(II), Fe(III), Co(II), and Ni(II) chelates with three quinolinol sulfonamides have been prepared and characterized. Characterization of the solids so obtained was accomplished by elemental analysis, electronic and ir spectra, and conductivity measurements. It was found that the sulfonamide ligands act as monobasic bidentate ON donors. The bonding sites are ascertained, and the complexes were all six-coordinate assuming a distorted octahedral geometry. It was identified that the metal chelates possess enhanced antibacterial and antifungal activities relative to the free ligands.

References

Mar 1, 1953·Il Farmaco; edizione pratica·U GALLO

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Citations

Dec 15, 2011·Biological Trace Element Research·Xu LiDong-Cai Guo
Jan 1, 1992·Journal of Chemical Technology and Biotechnology·M F el-ZohryM A Abd-Alla
May 1, 2019·Current Medicinal Chemistry·Natalia V LoginovaGenrikh I Polozov

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