Sonic hedgehog as a chemoattractant for adult NPCs.

Cell Adhesion & Migration
Catherine Hong Huan Hor, Bor Luen Tang

Abstract

The developmental morphogen Sonic hedgehog (Shh) is well known for its role in modulating the proliferation and survival of neural progenitor cells in the developing mouse brain. A recent report now showed that Shh could regulate the migration of neuroblast in the adult subventricular zone (SVZ) along the rostral migratory stream (RMS) to the olfactory bulb, by functioning as a chemoattractant. Functions of Shh in regulating the migration and survival of neural progenitor cells in the adult central nervous system are suggestive of its potential roles in neural regeneration and CNS oncogenesis.

References

Jan 30, 2002·Trends in Neurosciences·Elisa Martí, Paola Bovolenta
Feb 2, 2002·Nature Reviews. Neuroscience·Ariel Ruiz i AltabaNadia Dahmane
Dec 7, 2002·Nature Neuroscience·Karen LaiDavid V Schaffer
Sep 23, 2003·Developmental Biology·Artem JarovClaire Fournier-Thibault
Dec 18, 2004·Development·Verónica PalmaAriel Ruiz i Altaba
Jun 7, 2005·Developmental Biology·Leigh Wilson, Malcolm Maden
Aug 23, 2005·Brain Research. Brain Research Reviews·Cristina Sánchez-CamachoPaola Bovolenta
Jun 1, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Francesca Balordi, Gord Fishell
Dec 17, 2008·Developmental Cell·Jin Jiang, Chi-Chung Hui
Jun 27, 2009·Annual Review of Neuroscience·Arnold Kriegstein, Arturo Alvarez-Buylla

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Citations

Jan 29, 2011·Human Molecular Genetics·David CheishviliAharon Razin
Jun 23, 2010·Annual Review of Cell and Developmental Biology·John R Couchman
Oct 18, 2012·Archives of Biochemistry and Biophysics·Eva PorlanSacri R Ferrón
Mar 22, 2014·The European Journal of Neuroscience·Omari S KhalilTrevor W Stone
Jun 11, 2014·Developmental Neurobiology·Laura PerssonRosalind A Segal
May 31, 2014·Integrative Biology : Quantitative Biosciences From Nano to Macro·Aline M ThomasLonnie D Shea
Aug 28, 2019·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Ana Rita TunaMaria Vaz Pato
Jun 1, 2011·Virchows Archiv : an International Journal of Pathology·Christoph Köhler

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