Sonographic carotid plaque morphologic characteristics and vascular risk factors: results from a population study

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Edoardo VicenziniGian Luigi Lenzi

Abstract

The role of vascular risk factors in atherosclerosis development is well established, whereas risk factors involved in determining plaque vulnerability are still a matter of debate. We investigated the vascular risk factor distribution in patients with carotid plaques. We consecutively assessed sonographic plaque morphologic characteristics, the degree of stenosis, and the common carotid artery intima-media thickness (IMT) in 1655 patients. Demographic data, a documented history of symptomatic cerebrovascular disease (CVD), and the presence of vascular risk factors were collected. According to literature, heterogeneous hypoechoic plaques with an irregular surface or ulcerations and those with a severe degree of stenosis (>or=70%) have been considered "complex" plaques at "major" risk of stroke; homogeneous hyperechoic plaques with smooth surface lesions have been considered "simple" plaques at minor risk. Univariate analysis showed that all vascular risk factors were associated with the presence of carotid atherosclerotic lesions. Multiple logistic regression showed an independent association of hypertension and diabetes with complex plaques, which also had a thicker IMT. A history of CVD was observed more frequently in complex...Continue Reading

References

Jan 1, 1990·Ultrasound in Medicine & Biology·B WidderJ Vollmar
Sep 1, 1990·Archives of Neurology·N M BornsteinJ W Norris
Nov 1, 1985·Ultrasound in Medicine & Biology·D A RatliffA D Chant
Jun 22, 1999·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·G M BiasiA N Nicolaides
Jan 18, 2003·Lancet·P M RothwellUNKNOWN Carotid Endarterectomy Trialists' Collaboration
Feb 8, 2003·European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology·Christian DenzelWerner Lang
Jan 20, 2004·Cerebrovascular Diseases·Michael G Hennerici
Mar 6, 2004·Stroke; a Journal of Cerebral Circulation·Rolf KernStephen Meairs
Apr 28, 2004·Neurology·William J Powers
Feb 25, 2005·Current Atherosclerosis Reports·Stéphane CarlierMorteza Naghavi
Jul 18, 2006·Journal of the American College of Cardiology·Steven B Feinstein
Oct 13, 2006·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Liz Warburton, Jonathan Gillard
Nov 25, 2006·Cerebrovascular Diseases·Gian Luigi Lenzi, Edoardo Vicenzini
Jan 11, 2007·Journal of Vascular Surgery·Benjamin J DunmoreNicholas P J Brindle
May 26, 2007·Stroke; a Journal of Cerebral Circulation·Gerd OstlingIsabel Gonçalves

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Citations

Oct 23, 2012·Stroke; a Journal of Cerebral Circulation·Adam Domonkos TarnokiGiuseppe Schillaci
Jan 1, 2009·Expert Opinion on Medical Diagnostics·Paul Anaya
Jul 17, 2010·AJNR. American Journal of Neuroradiology·L SabaG Mallarini
Jan 19, 2021·Vascular and Endovascular Surgery·Stavros K KakkosIoannis Tsolakis

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