Sonographic Features of Ductal Carcinoma In Situ of the Breast With Microinvasion: Correlation With Clinicopathologic Findings and Biomarkers

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Jie-Jie YaoXiao-Song Chen

Abstract

To compare the sonographic results, clinicopathologic characteristics, and biomarkers in pure ductal carcinoma in situ (DCIS) of the breast and DCIS with microinvasion. A total of 218 patients with pathologically proven DCIS based on sonography in our hospital (2009-2013) were retrospectively enrolled. Clinicopathologic characteristics and biomarkers were examined. Grayscale sonographic results were investigated according to the American College of Radiology Breast Imaging Reporting and Data System lexicon, and color Doppler sonography was used to assess the vascularization distribution and degree. All variables were compared by univariate and multivariate logistic regression analyses. All patients were female, with a mean age of 55.3 years (range, 32-78 years). One hundred sixty patients with 160 lesions had pure DCIS, and 58 patients with 58 lesions had DCIS with microinvasion. Ductal carcinoma in situ with microinvasion was more likely to have sentinel lymph node metastases, larger tumors, a higher tumor grade, human epidermal growth factor receptor 2 positivity, and a high Ki-67 index (all P < .05). Univariate analysis showed that DCIS with microinvasion was more likely to be hypoechoic with microcalcifications, have a mixe...Continue Reading

References

Mar 1, 1992·The British Journal of Surgery·J M DixonU Chetty
May 6, 1995·Lancet·M J SilversteinD J Slamon
Mar 16, 2002·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Woo Kyung MoonJung-Gi Im
Sep 21, 2002·Journal of Clinical Ultrasound : JCU·Sheen-Woo LeeSoo Mee Lim
Nov 7, 2002·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Wei Tse YangJenny Chang
Aug 20, 2005·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Takeshi NagashimaMasaru Miyazaki
Jan 21, 2009·Breast Cancer Research and Treatment·Lei FanZhi-Ming Shao
Apr 22, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Frédérique Penault-LlorcaHenri Roché
May 14, 2010·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Sarah E Pinder
Feb 12, 2013·Journal of Ultrasound·Paolo BusilacchiClaudio Ferranti
Jun 25, 2013·American Journal of Surgery·Gloria R SueAnees B Chagpar
Aug 21, 2013·Journal of Clinical Ultrasound : JCU·Mi Hee LeeSoo Yeon Hahn
Apr 26, 2014·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Man ChenXiao-chun Fei

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Citations

Mar 3, 2020·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Jia-Wei LiCai Chang
Dec 26, 2019·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yu-Yang TongJia-Wei Li
Aug 10, 2019·Molecular and Clinical Oncology·Hongli WangFengxi Su
Dec 18, 2020·Journal of Applied Clinical Medical Physics·Sijia HanGuijin He

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