Sonographic features of thyroid nodules that may help distinguish clinically atypical subacute thyroiditis from thyroid malignancy

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Fu-shun PanXiao-xi Li

Abstract

The purpose of this study was to evaluate sonographic features for distinguishing clinically atypical subacute thyroiditis from malignant thyroid nodules. A total of 165 hypoechoic thyroid nodules without calcification in 135 patients with histologic diagnosis were included in this study. These nodules were classified into 2 groups: a thyroiditis group (55 nodules in 36 patients) and a malignancy group (110 nodules in 99 patients). The sonographic features of the groups were retrospectively reviewed. No significant differences were detected for the variables of marked echogenicity, a taller-than-wide shape, and mixed vascularity. However, a poorly defined margin was detected more frequently in the thyroiditis group than the malignancy group (P < .05); it yielded a high capability for differential diagnosis of atypical subacute thyroiditis, with sensitivity and specificity of 87.3% and 80.9%, respectively. Centripetal reduction echogenicity was observed exclusively in the thyroiditis group, with high specificity (100%) but low sensitivity (21.8%) for atypical subacute thyroiditis diagnosis. All of the thyroiditis nodules with a positive color signal showed noninternal vascularity (negative predictive value, 100%). There is a con...Continue Reading

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Citations

Aug 19, 2016·Acta chirurgica Belgica·Corinne JonasJulian E Donckier
Mar 30, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Margaret Yee Wah LeeWai Yin Wong
Oct 1, 2015·Archives of Endocrinology and Metabolism·Raisa Bressan ValentiniErika Laurini Souza Meyer
Oct 8, 2020·Current Problems in Diagnostic Radiology·Gilbert H DanielsGiuseppe Barbesino
May 6, 2021·Reviews in Endocrine & Metabolic Disorders·Magdalena Stasiak, Andrzej Lewiński
Jun 10, 2021·Acta Radiologica Open·Hee Joong LimDong Young Kim

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