Sonographic screening to detect fetal cardiac anomalies: a 5-year experience with 111 abnormal cases

Obstetrics and Gynecology
J S KirkE Weinhouse

Abstract

To determine whether there is a difference between the types of cardiac lesions detected as abnormal prenatally and those that are not detected. Consecutive fetuses at 14 weeks' gestation or more were scanned in our unit from February 1990 through July 1995 and later were delivered at our hospital. Outcome information was obtained from neonatal echocardiograms and autopsies. Our results were compared to sensitivities for individual cardiac lesions based on pooled data from studies published previously. There were 111 fetuses with cardiac anomalies, of which 73 (66%) were identified correctly as abnormal prenatally. Sensitivities for the most common cardiac lesions were as follows: 87% atrioventricular septal (endocardial cushion) defects, 65% tetralogy of Fallot, 63% transposition of the great arteries, 50% aortic coarctation, and 44% isolated ventricular septal defects. The lesions that went undetected most frequently were isolated septal defects (n = 17); most of these were ventricular and small or moderate in size. Based on our sensitivities and those calculated from previous studies, the fetal cardiac lesions with the highest detection rates involve hypoplastic ventricles and atrioventricular septal defects, followed by les...Continue Reading

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Citations

Jun 1, 1999·Comprehensive Therapy·L A IzquierdoG Holmes
Feb 5, 1999·Obstetrics and Gynecology·J S KirkE Weinhouse
Feb 22, 2012·Clinical Obstetrics and Gynecology·Luís F GonçalvesWesley Lee
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Sep 9, 2005·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Luís F GonçalvesBetsy Beyer
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Mar 8, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ran SvirskyYuval Yaron
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Nov 11, 2003·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·UNKNOWN American Institute of Ultrasound in Medicine
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