Sonography of renal transplants in dogs: the effect of acute tubular necrosis, cyclosporine nephrotoxicity, and acute rejection on resistive index and renal length

AJR. American Journal of Roentgenology
M A PozniakR Stratta


Results of studies on the accuracy of the resistive index as a predictor of acute renal transplant rejection have varied widely. Clinical evaluations are limited by the inability to control the numerous coincidental factors that affect vascular resistance. We performed a controlled study in dogs to isolate the effects of acute tubular necrosis, cyclosporine toxicity, and acute rejection on the resistive index, and to compare them with a population of normal control subjects. By doing so, we hoped to identify the patterns of change in the resistive index over time and possibly explain the wide spectrum of resistive index data reported in the literature. Resistive index, a parameter calculated from relative systolic and diastolic velocity, indicates parenchymal resistance to perfusion. Since an increase in renal length also has been reported useful in predicting rejection, we studied changes in length in each of the isolated conditions. The normal control group (four dogs) had heterotopic autotransplantation with minimal cold ischemic time. The acute tubular necrosis group (six dogs) had heterotopic autotransplantation with 1 hr of warm ischemic time. The cyclosporine toxicity group (four dogs) was allowed approximately 3 months ...Continue Reading


Feb 1, 2011·Journal of Feline Medicine and Surgery·Cibele F Carvalho, Maria C Chammas
Sep 25, 2002·Transplantation Proceedings·A AktasR Emiroglu
Dec 3, 2014·Radiologic Clinics of North America·Shuchi K RodgersMindy M Horrow
Jun 11, 2005·Research in Veterinary Science·Lee M KomaLeonie Scholtz
May 31, 2012·Emergency Radiology·Matthew T Heller, Alexander Hattoum
Jan 1, 1997·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·T G NylandE R Wisner
Aug 15, 2006·Burns : Journal of the International Society for Burn Injuries·Toshiyuki KuwaLeopoldo C Cancio
Mar 11, 2008·Radiologic Clinics of North America·Anand K Singh, Dushyant V Sahani
Jan 2, 2004·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Krista B HallingDaniel Grossman
Oct 23, 2003·Ultrasound Quarterly·Grant M Baxter
Oct 16, 1999·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·J A ChurchillD J Polzin
Oct 28, 2005·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Lee M KomaPaul Bland-van den Berg
May 14, 1999·Journal of Clinical Ultrasound : JCU·M K SidhuJ D Scandling

Related Concepts

Canis familiaris
Graft Rejection
Kidney Tubular Necrosis, Acute
Postoperative Complications
Renal Blood Flow
Pulmonary Vascular Resistance
Kidney Transplantation

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Computational Methods for Protein Structures

Computational methods employing machine learning algorithms are powerful tools that can be used to predict the effect of mutations on protein structure. This is important in neurodegenerative disorders, where some mutations can cause the formation of toxic protein aggregations. This feed follows the latests insights into the relationships between mutation and protein structure leading to better understanding of disease.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.

Related Papers

Poultry Science
T S NelsonM M Campbell
Radiographics : a Review Publication of the Radiological Society of North America, Inc
Jason N NixonMarguerite T Parisi
© 2021 Meta ULC. All rights reserved