PMID: 8453159Mar 1, 1993Paper

Sorbitol content of selected oral liquids

The Annals of Pharmacotherapy
D M LutomskiJ E Martin

Abstract

Excipients in pharmaceuticals usually are considered inert, and may be overlooked in the differential diagnosis of diarrhea. Sorbitol-containing medicinal liquids are capable of inducing osmotic diarrhea. We reviewed the oral liquids in our formulary to determine their sorbitol content and to evaluate the availability of this information. The oral liquids stocked by our hospital were determined through a computer search and manual inspection of the pharmacy storeroom. Three common sources of drug information were consulted to determine each product's sorbitol content: manufacturers' product information, American Hospital Formulary Service (AHFS) Drug Information 91, and Facts and Comparisons Drug Information. We then contacted each manufacturer by mail or telephone to verify the information. The study was conducted at the University of Cincinnati Hospital, a tertiary-care, teaching hospital. A total of 129 products (98 chemical entities) were reviewed. Fifty-four (42 percent) of the products examined contained sorbitol. The frequency of sorbitol presence by liquid type was: solutions (33 percent), suspensions (43 percent), syrups (59 percent), elixirs (43 percent), concentrates (67 percent), drops (33 percent), tinctures (0 per...Continue Reading

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Citations

Nov 3, 2005·Brain Injury : [BI]·C T KimS W Kim
Sep 1, 1993·The Annals of Pharmacotherapy·K R JohnstonM H Andritz
Aug 1, 1994·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·B MagnusonB Young
Apr 18, 2000·Nursing Research·D Z BlissD N Gerding
Apr 23, 2008·Journal of Advanced Nursing·Melissa A L ThorsonKay Savik
Dec 5, 2008·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Nancy Toedter Williams
Jan 23, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Nicola Ward
Jul 24, 2015·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Michelle Kozeniecki, Rebecca Fritzshall
Jan 20, 2016·Expert Opinion on Drug Delivery·Wouter F W KappelleFrank P Vleggaar
Jun 1, 1996·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·M F Shepherd, P A Felt-Gunderson
Feb 5, 2010·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Imad F BtaicheMichael D Kraft
Dec 28, 2016·Journal of Clinical Gastroenterology·Nissy A PhilipCapecomorin S Pitchumoni
Dec 25, 2003·The Proceedings of the Nutrition Society·Sharon M Madigan
Oct 14, 2019·Current Nutrition Reports·Kathryn S BandyStephen A McClave
Oct 19, 2006·Pharmaceutical Research·M-L ChenA S Hussain
Aug 1, 1994·The American Journal of Medicine·K R JohnstonM H Andritz
Apr 1, 1996·Pediatric Clinics of North America·T J Sferra, L A Heitlinger

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