Sorsby's fundus dystrophy. A light and electron microscopic study.

Ophthalmology
M R CaponA C Bird

Abstract

The light and electron microscopic changes in both eyes of a patient with Sorsby's fundus dystrophy are reported. The most striking finding was a 30-microns thick deposit present within Bruch's membrane that stained positive for lipids. The deposit has several unique features when compared with those found in other retinal dystrophies and in aged eyes. In addition, there was gross loss of the outer retina, the retinal pigment epithelium was discontinuous, and there was atrophy of the choriocapillaris. These findings are discussed in relation to the published clinical observations of other members of this pedigree.

References

Nov 1, 1977·American Journal of Ophthalmology·A F Deutman, F Lion
Nov 15, 1985·American Journal of Ophthalmology·L Feeney-Burns, M R Ellersieck
Mar 1, 1971·Archives of Ophthalmology·E M Van BuskirkE Friedman

❮ Previous
Next ❯

Citations

Mar 31, 1998·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Y ZengJ Bennett
Jan 1, 1995·International Ophthalmology·J ZhaoP F Lopez
Jun 1, 1994·Nature Genetics·B H WeberC C Ewing
Sep 1, 1995·Nature Genetics·S G JacobsonE M Stone
Aug 1, 1996·Australian and New Zealand Journal of Ophthalmology·A T Moore, K Evans
May 11, 2006·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Axel Petzold, Gordon T Plant
Dec 24, 2010·Clinical Chemistry and Laboratory Medicine : CCLM·Haris KokotasMichael B Petersen
Dec 3, 2013·Progress in Retinal and Eye Research·Nicole T M SaksensCarel B Hoyng
Mar 1, 1995·Journal of Medical Genetics·C Y GregoryS S Bhattacharya
Sep 1, 1993·The British Journal of Ophthalmology·R L SteinmetzA C Bird
Jun 30, 2000·The British Journal of Ophthalmology·J J AssinkF Meire
Sep 10, 2003·Journal of Medical Genetics·M MichaelidesA T Moore
Jul 14, 2006·The British Journal of Ophthalmology·M A MajidA D Dick
Sep 3, 2010·The Journal of Clinical Investigation·Alan C Bird
May 14, 1998·Molecular Aspects of Medicine·A TaylorM Obin
May 23, 2009·Clinical & Experimental Ophthalmology·Joshua A SzentalRobyn H Guymer
Sep 23, 2006·American Journal of Ophthalmology·Ruth J LinDouglas Vollrath
May 27, 2008·American Journal of Ophthalmology·Sobha SivaprasadAdnan Tufail
May 1, 1997·American Journal of Ophthalmology·R Y KimJ L Olson
Jun 16, 2011·PloS One·Andrew J ChildsPhilippa T K Saunders
Mar 1, 1992·The British Journal of Ophthalmology·A C Bird
Jan 1, 1996·Documenta Ophthalmologica. Advances in Ophthalmology·M P ClarkeS McDonnell
Sep 8, 2016·Scientific Reports·Isabelle MeunierChristian P Hamel
Sep 8, 2017·Proceedings of the National Academy of Sciences of the United States of America·Chad A GallowayRuchira Singh
Sep 21, 2020·The British Journal of Ophthalmology·Alan Bird
Jul 28, 2020·Ophthalmic Genetics·Meghan J DeBenedictisBela Anand-Apte
Sep 1, 1995·Nature Medicine·T S Acott, R G Weleber
Jul 27, 2000·Journal of Cellular Physiology·P A Campochiaro
Apr 17, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·A LommatzschD Pauleikhoff

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ophthalmology
W K HamiltonJ D Carruthers
Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
M MäntyjärviA Klemetti
The British Journal of Ophthalmology
A A BergenM J van Schooneveld
The British Journal of Ophthalmology
A SORSBY, M E J MASON
© 2022 Meta ULC. All rights reserved