PMID: 11929598Apr 4, 2002Paper

Sorting out signals in fly endosomes

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Helmut Krämer

Abstract

Ligands and receptors that mediate cell-cell interactions during development are removed from the cell surface by endocytosis. Subsequently, many of these internalized proteins are detected in multivesicular bodies (MVBs). Recent work in different organisms has elucidated some aspects of MVB biogenesis and trafficking. This review discusses some intriguing links between these findings, the sorting of proteins in endocytic trafficking, and the regulation of signaling pathways in Drosophila.

References

Feb 1, 1997·Current Opinion in Neurobiology·M VervoortA Ghysen
Jun 1, 1997·Current Opinion in Neurobiology·O Cremona, P De Camilli
Jul 1, 1997·Physiological Reviews·S MukherjeeF R Maxfield
Jan 27, 1998·Developmental Biology·L SeugnetM Haenlin
Jun 24, 1998·Genes & Development·I Greenwald
Aug 26, 1998·Trends in Cell Biology·V LloydH Krämer
Jan 16, 1999·Current Biology : CB·M Fernandez-BorjaJ Neefjes
Nov 24, 1999·Nature Cell Biology·M Asaoka-TaguchiS Kobayashi
Jul 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·C UngermannW Wickner
Dec 9, 2000·Developmental Biology·J S Mumm, R Kopan
Dec 21, 2000·The Journal of Cell Biology·E SantoliniP P Di Fiore
Mar 27, 2001·Nature Reviews. Molecular Cell Biology·L Hicke
Mar 27, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·C Mullins, J S Bonifacino
Jul 14, 2001·Molecular Biology of the Cell·M HuizingR E Boissy
Oct 5, 2001·Nature Reviews. Molecular Cell Biology·J Gruenberg
Nov 7, 2001·Current Biology : CB·E YehG L Boulianne
Mar 1, 1983·Wilhelm Roux's Archives of Developmental Biology·Ruth LehmannJosé A Campos-Ortega

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Citations

Dec 24, 2002·Trends in Cell Biology·Owen PornillosWesley I Sundquist
Jun 12, 2008·Annual Review of Genomics and Human Genetics·Marjan HuizingWilliam A Gahl
Jun 27, 2009·PLoS Genetics·Sandra Fausia SoukupDavid Gubb
Aug 6, 2003·The Journal of Cell Biology·Owen PornillosWesley I Sundquist
Jul 13, 2011·The Journal of Cell Biology·Dinari A HarrisRichard W Carthew
Mar 16, 2007·Matrix Biology : Journal of the International Society for Matrix Biology·Bernard MoussianHeinz Schwarz
Dec 15, 2010·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Stephen Klusza, Wu-Min Deng
Mar 19, 2003·Differentiation; Research in Biological Diversity·Mariusz K JaglarzSzczepan M Biliński
Apr 1, 2004·Molecular Cell·Wesley I SundquistChristopher P Hill
Jan 11, 2011·Progress in Neurobiology·Christopher S Von Bartheld, Amy L Altick
Jan 26, 2018·The Journal of Experimental Biology·Carlos Tejeda-GuzmánFanis Missirlis
Jun 5, 2003·American Journal of Physiology. Lung Cellular and Molecular Physiology·Timothy A LyerlaRichard T Swank

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