PMID: 2487773Oct 1, 1989Paper

South American rattlesnake venom: its hemolytic power

Revista Da Sociedade Brasileira De Medicina Tropical
E G de LimaC J Laure

Abstract

The hemolytic power of rattlesnake venom (Crotalus durissus terrificus) was studied. A high percentage of sample with negative hemolytic power was detected when sheep red blood cells were used. A large number of venoms with hemolytic power, though with a low hemolysis percentage, were detected when liquid, recently extracted venom was used. When crystallized venom was used under the same experimental conditions, a higher percentage of positivity for hemolysis was obtained. When the results obtained on agar plates were compared to those obtained in test tubes, a large number of animals with a higher percentage of hemolysis were detected, though this value was not proportional to the number of animals showing positive plate hemolysis. When the hemolytic power of these venoms was tested on human red blood cells, a large percentage of animals with venoms having a low hemolytic power was also detected. Hemolytic power was much greater when human red blood cells were tested with crystallized venom. The preparation of red blood cells also had an important effect and the use of red blood cells from defibrinated blood is recommended. We conclude that rattlesnake venom has hemolytic power that increases when the venom is crystallized. Re...Continue Reading

References

Jan 1, 1987·Toxicon : Official Journal of the International Society on Toxinology·C L Ownby, C R Geren
Jan 1, 1987·Revista Da Sociedade Brasileira De Medicina Tropical·E Garcia-Lima, C J Laure
Jul 28, 1972·Science·E Habermann
Nov 1, 1967·Biochemical Pharmacology·A T TuS Ganthavorn
Jan 1, 1980·Toxicon : Official Journal of the International Society on Toxinology·S Y Huang, J C Perez
Oct 1, 1964·Toxicon : Official Journal of the International Society on Toxinology·C R GOUCHER, H H FLOWERS

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Citations

Sep 2, 1998·Toxicon : Official Journal of the International Society on Toxinology·A M MartinsM C Fonteles
Oct 11, 2001·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·H S MonteiroM C Fonteles

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