Space GlucoseControl system for blood glucose control in intensive care patients--a European multicentre observational study

BMC Anesthesiology
Jan BlahaJoel Starkopf

Abstract

Glycaemia control (GC) remains an important therapeutic goal in critically ill patients. The enhanced Model Predictive Control (eMPC) algorithm, which models the behaviour of blood glucose (BG) and insulin sensitivity in individual ICU patients with variable blood samples, is an effective, clinically proven computer based protocol successfully tested at multiple institutions on medical and surgical patients with different nutritional protocols. eMPC has been integrated into the B.Braun Space GlucoseControl system (SGC), which allows direct data communication between pumps and microprocessor. The present study was undertaken to assess the clinical performance and safety of the SGC for glycaemia control in critically ill patients under routine conditions in different ICU settings and with various nutritional protocols. The study endpoints were the percentage of time the BG was within the target range 4.4 - 8.3 mmol.l(-1), the frequency of hypoglycaemic episodes, adherence to the advice of the SGC and BG measurement intervals. BG was monitored, and insulin was given as a continuous infusion according to the advice of the SGC. Nutritional management (enteral, parenteral or both) was carried out at the discretion of each centre. 17 ...Continue Reading

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Citations

Aug 4, 2018·Critical Care : the Official Journal of the Critical Care Forum·J Geoffrey ChaseJean-Charles Preiser
Apr 20, 2019·Emerging Infectious Diseases·Audrey Dubot-PérèsPaul N Newton
Mar 30, 2020·Journal of Clinical Monitoring and Computing·Aude de WattevilleClaudia-Paula Heidegger
Jul 2, 2020·Medical Devices : Evidence and Research·Athirah Abdul RazakJames Geoffrey Chase
May 9, 2021·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·María-Dolores González-CaroJosé Garnacho-Montero
May 13, 2021·Computer Methods and Programs in Biomedicine·M van den BoornP H J van der Voort

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Clinical Trials Mentioned

NCT01523665

Software Mentioned

EndoTool Glucose Management System
SPSS
Glucommander
Space GlucoseControl
SPRINT
SpaceCOM
SpaceControl
EndoTool
SPSS®

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