SPAKling insight into blood pressure regulation.

EMBO Molecular Medicine
María Castañeda-Bueno, Gerardo Gamba

Abstract

Arterial hypertension is one of the most important health problems in industrialized cities. Blood pressure levels are influenced by renal salt handling and salt reabsorption in the kidney. In this Closeup, Castañeda-Bueno and Gamba discuss the work from Alessi and coworkers on the in vivo roles of the SPAK kinase in defining blood pressure levels.

References

May 16, 2003·JAMA : the Journal of the American Medical Association·Aram V ChobanianUNKNOWN National High Blood Pressure Education Program Coordinating Committee
Oct 10, 2008·Journal of Cell Science·Ciaran Richardson, Dario R Alessi
Dec 31, 2008·Proceedings of the National Academy of Sciences of the United States of America·Ying WangYen-Pei C Chang
May 29, 2009·American Journal of Physiology. Renal Physiology·Gerardo Gamba
Jan 22, 2010·EMBO Molecular Medicine·Fatema H RafiqiDario R Alessi

❮ Previous
Next ❯

Citations

Oct 16, 2014·The Journal of Membrane Biology·Bernat ElviraFlorian Lang
Aug 28, 2014·The Journal of Membrane Biology·Bernat ElviraFlorian Lang
Aug 4, 2015·The Journal of Membrane Biology·Abeer AbousaabFlorian Lang
Jul 26, 2015·Biochemistry·Clinton A TaylorMelanie H Cobb
Dec 14, 2012·Kidney & Blood Pressure Research·Ganesh PathareFlorian Lang
Dec 6, 2014·American Journal of Physiology. Renal Physiology·Chih-Jen ChengChou-Long Huang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Current Opinion in Nephrology and Hypertension
Annie Mercier-Zuber, Kevin M O'Shaughnessy
Current Opinion in Nephrology and Hypertension
Mark Glover, Kevin M O'Shaughnessy
© 2021 Meta ULC. All rights reserved