Sparse Ordinal Logistic Regression and Its Application to Brain Decoding

Frontiers in Neuroinformatics
Emi SatakeYukiyasu Kamitani

Abstract

Brain decoding with multivariate classification and regression has provided a powerful framework for characterizing information encoded in population neural activity. Classification and regression models are respectively used to predict discrete and continuous variables of interest. However, cognitive and behavioral parameters that we wish to decode are often ordinal variables whose values are discrete but ordered, such as subjective ratings. To date, there is no established method of predicting ordinal variables in brain decoding. In this study, we present a new algorithm, sparse ordinal logistic regression (SOLR), that combines ordinal logistic regression with Bayesian sparse weight estimation. We found that, in both simulation and analyses using real functional magnetic resonance imaging (fMRI) data, SOLR outperformed ordinal logistic regression with non-sparse regularization, indicating that sparseness leads to better decoding performance. SOLR also outperformed classification and linear regression models with the same type of sparseness, indicating the advantage of the modeling tailored to ordinal outputs. Our results suggest that SOLR provides a principled and effective method of decoding ordinal variables.

References

Apr 27, 2005·Nature Neuroscience·Yukiyasu Kamitani, Frank Tong
Jun 7, 2006·Current Biology : CB·Yukiyasu Kamitani, Frank Tong
Jun 23, 2006·Nature Reviews. Neuroscience·John-Dylan Haynes, Geraint Rees
Aug 11, 2006·Trends in Cognitive Sciences·Kenneth A NormanJames V Haxby
Dec 17, 2008·NeuroImage·Francisco PereiraMatthew Botvinick
Mar 10, 2009·Current Biology : CB·Noël StaerenElia Formisano
Mar 2, 2010·NeuroImage·Srikanth RyaliVinod Menon
Mar 30, 2010·NeuroImage·Carlton ChuJohn Ashburner
Jul 2, 2011·Frontiers in Neuroscience·Jessica R CohenRussell A Poldrack
Aug 2, 2011·NeuroImage·Laura B BaucomSvetlana V Shinkareva
Aug 3, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Akiko NishioHidehiko Komatsu
Jul 13, 2013·Frontiers in Neuroinformatics·Russell A PoldrackMichael P Milham
Mar 3, 2015·American Economic Journal. Microeconomics·Alec SmithAntonio Rangel
Feb 10, 2016·Frontiers in Neuroinformatics·Makoto TakemiyaYukiyasu Kamitani

❮ Previous
Next ❯

Software Mentioned

SMLR
SOLR
L2OLR
SLiR
MATLAB
OLR

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.