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Spasmolytic action of histamine in airway smooth muscle of horse

Agents and Actions

Apr 1, 1978

N Chand, P Eyre

Abstract

Histamine, 2-methylhistamine (a specific H1-agonist), 5-HT, PGF2alpha, SRS-A, bradykinin (BK) and carbachol contract bronchial and tracheal smooth muscles of the horse. Isoprenaline, PGE1, E2, dimaprit and 4-methylhistamine (last two = specific H2-agonists) relaxed airways which were pa...read more

Mentioned in this Paper

Histamine Measurement
KNG1
Bronchial System
Pyrilamine
Respiratory Tract Structure
Metiamide Monohydrochloride
Osmosin
Serotonin
Antagonist Muscle Action
Tagamet
Paper Details
References
  • References21
  • Citations25
123
  • References21
  • Citations25
123

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Spasmolytic action of histamine in airway smooth muscle of horse

Agents and Actions

Apr 1, 1978

N Chand, P Eyre

PMID: 665431

DOI: 10.1007/bf01966602

Abstract

Histamine, 2-methylhistamine (a specific H1-agonist), 5-HT, PGF2alpha, SRS-A, bradykinin (BK) and carbachol contract bronchial and tracheal smooth muscles of the horse. Isoprenaline, PGE1, E2, dimaprit and 4-methylhistamine (last two = specific H2-agonists) relaxed airways which were pa...read more

Mentioned in this Paper

Histamine Measurement
KNG1
Bronchial System
Pyrilamine
Respiratory Tract Structure
Metiamide Monohydrochloride
Osmosin
Serotonin
Antagonist Muscle Action
Tagamet

Similar Papers Found In These Feeds

Inotropic Agents & Heart Disease

Inotropic agents alter the force or energy of muscular contractions. Negatively inotropic agents weaken the force of muscular contractions. Positively inotropic agents increase the strength of muscular contraction. Inotropic agents are used in hospitalized patients with acute decompensated heart failure, with reduced left ventricular ejection fraction and with signs of end-organ dysfunction in the setting of a low cardiac output, or with severe systolic heart failure awaiting heart transplant to maintain hemodynamic stability or as a bridge to decision. Discover the latest research on inotrpic agents and heart diseases here.

Related Papers

The Journal of Pharmacy and Pharmacology

The presence of inhibitory histamine H-2-receptors in guinea-pig tracheobronchial muscle

The Journal of Pharmacy and PharmacologyMarch 1, 1978
D T OkpakoP Eyre
Agents and Actions

Atypical (relaxant) response to histamine in cat bronchus

Agents and ActionsJuly 1, 1977
N Chand, P Eyre
Paper Details
References
  • References21
  • Citations25
123
  • References21
  • Citations25
123
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