Spasticity following spinal cord injury

Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
Tiina RekandMarit Grønning

Abstract

Up to 70% of patients with spinal cord injuries develop spasticity. The main aim of the paper is to provide an overview of spasticity management, primarily in patients with spinal cord injuries. The article is based on literature searches in PubMed using the keyphrases «spasticity» and «spasticity AND spinal cord injury», and own clinical experience and research. Spasticity may be general, regional or localised. Factors such as an over-filled bladder, obstipation, acute infections, syringomyelia or bone fractures may substantially influence the degree of spasticity and must be determined. An assessment of the clinical and functional consequences for the patient is decisive before management. Active exercise, physiotherapy and peroral drugs are the simplest and cheapest options. Baclofen is the only centrally acting spasmolytic registered in Norway and is the first choice for peroral treatment. Benzodiazepines can also be used. The effect of the tablets is generally limited and there are often pronounced side effects. Local spasticity can be treated with botulinum toxin injections. The effect is time-limited and the treatment must be repeated. International guidelines recommend a combination of botulinum toxin injections and phy...Continue Reading

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Citations

Aug 21, 2013·Archives of Physical Medicine and Rehabilitation·Julius A BishopCatherine M Curtin
Mar 22, 2014·Frontiers in Systems Neuroscience·Lucas SantosSamuel Deadwyler
Oct 9, 2016·Archives of Physical Medicine and Rehabilitation·Frederico Ribeiro NetoRodrigo Rodrigues Gomes Costa
Jun 6, 2018·The Journal of Spinal Cord Medicine·Ramiro Palazón-GarcíaAna María Benavente-Valdepeñas
Sep 12, 2015·Annals of Rehabilitation Medicine·Hyun BangKeewon Kim
Feb 5, 2014·Stem Cells Translational Medicine·Danuta JarochaMarcin Majka
May 15, 2020·The Journal of Spinal Cord Medicine·Anas R AlashramNicola Biagio Mercuri
Jul 11, 2018·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Amir EftekharJonathan R Wolpaw
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Nov 17, 2020·Topics in Spinal Cord Injury Rehabilitation·Philippines CabahugJesse A Lieberman
Aug 31, 2021·Topics in Spinal Cord Injury Rehabilitation·Frederico Ribeiro NetoRodrigo L Carregaro

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