PMID: 9178259Apr 1, 1997Paper

Spatial and temporal pattern of expression of the wingless and engrailed genes in the adult antenna is regulated by age-dependent mechanisms

Mechanisms of Development
Blanka Rogina, Stephen L Helfand

Abstract

The spatial and temporal pattern of expression of enhancer trap lines reporting on the wingless (wg) and engrailed (en) genes was characterized in the adult antenna of Drosophila melanogaster. The time courses of expression seen for wg and en, although different from each other, reveal a complex well-controlled pattern of temporal expression, providing evidence that regulatory mechanisms are preserved throughout the life span of the adult fly. Altering the life span demonstrates that the temporal patterns of expression of both wg and en are linked to life span. These studies suggest that the expression of wg and en in the adult antenna is controlled by age-dependent mechanisms.

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Citations

Jul 4, 2008·Invertebrate Neuroscience : in·Jonathan M Blagburn
Feb 12, 2002·Nature Reviews. Genetics·Stephen L Helfand, Sharon K Inouye
Aug 26, 2004·Proceedings of the National Academy of Sciences of the United States of America·Johannes H BauerStephen L Helfand
Jun 10, 1997·Proceedings of the National Academy of Sciences of the United States of America·B RoginaS L Helfand
Mar 2, 1999·Developmental Biology·V King, J Tower
Dec 18, 2001·Mechanisms of Development·Barry Hoopengardner, Stephen L Helfand
Oct 31, 2009·PLoS Computational Biology·Maksat AshyraliyevJohannes Jaeger
May 12, 2009·Mechanisms of Ageing and Development·Matthew A BedoukianJennifer Park
Oct 23, 1997·Science·C E Finch, R E Tanzi

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