Spatial assessment of Argentinean genetic admixture with geographical information systems

Forensic Science International. Genetics
Amalia Diaz-LacavaMax P Baur

Abstract

In recent years there has been much attention to Argentinean population stratification. We were interested in assessing population stratification from a geographical perspective and summarizing it in form of maps. We mapped the genetic admixture of the extant male population in central and northern Argentina on the basis of forensic Y-chromosomal haplotypes. We addressed the question which group of genetically similar individuals is predominant in this area. Haplotypes containing seven Y-chromosomal short tandem repeat polymorphisms (Y-STRs), also known as microsatellites - DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393 - were constructed for 145 individuals, recruited in 10 provinces. 97 distinct haplotypes were clustered into four clusters according to molecular distances. A genetic geostatistical analysis was conducted with the open-source geographical information system GRASS GIS. For each haplotype cluster, the according frequency was spatially interpolated over the total study area. Juxtaposing the interpolation surfaces, we screened point-wisely the maximal frequency as well as the label of the respective cluster. The screening results were combined in one summary map. We repeated this procedure for the second ...Continue Reading

References

Sep 26, 1997·Journal of Molecular Evolution·A Pérez-LezaunJ Bertranpetit
Jan 19, 2006·Annals of Human Biology·E L AlfaroC M Vullo
Jun 1, 2007·Forensic Science International. Genetics·Miguel MarinoDaniel Corach
Jan 12, 2010·Annals of Human Genetics·Daniel CorachManfred Kayser

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Citations

Oct 26, 2010·Forensic Science International. Genetics·Amalia Diaz-LacavaLutz Roewer
Aug 15, 2015·Genetics and Molecular Biology·Eduardo Javier López Soto, Cecilia Inés Catanesi
May 31, 2019·American Journal of Human Biology : the Official Journal of the Human Biology Council·Miguel A Alfonso-SánchezJosé A Peña
Nov 18, 2018·International Journal of Legal Medicine·J F FerragutA Picornell

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