Spatial dependency of Buruli ulcer prevalence on arsenic-enriched domains in Amansie West District, Ghana: implications for arsenic mediation in Mycobacterium ulcerans infection

International Journal of Health Geographics
Alfred A DukerMartin Hale

Abstract

BACKGROUND: In 1998, the World Health Organization recognized Buruli ulcer (BU), a human skin disease caused by Mycobacterium ulcerans (MU), as the third most prevalent mycobacterial disease. In Ghana, there have been more than 2000 reported cases in the last ten years; outbreaks have occurred in at least 90 of its 110 administrative districts. In one of the worst affected districts, Amansie West, there are arsenic-enriched surface environments resulting from the oxidation of arsenic-bearing minerals, occurring naturally in mineral deposits. RESULTS: Proximity analysis, carried out to determine spatial relationships between BU-affected areas and arsenic-enriched farmlands and arsenic-enriched drainage channels in the Amansie West District, showed that mean BU prevalence in settlements along arsenic-enriched drainages and within arsenic-enriched farmlands is greater than elsewhere. Furthermore, mean BU prevalence is greater along arsenic-enriched drainages than within arsenic-enriched farmlands. CONCLUSION: The results suggest that arsenic in the environment may play a contributory role in MU infection.

References

Mar 1, 1975·Leprosy Review·W M Meyers, D H Connor
Dec 1, 1991·International Journal of Epidemiology·J Hayman
Jan 1, 1985·Journal of Toxicology and Environmental Health·C AranyiF J Miller
Feb 1, 1980·Southern Medical Journal·W L Schoolmeester, D R White
Oct 1, 1994·Mutation Research·M E GonsebattP Ostrosky-Wegman
Jul 1, 1995·American Journal of Public Health·G E GlassE Israel
Dec 1, 1994·Human & Experimental Toxicology·G G García-VargasF De Matteis
Apr 1, 1995·Kekkaku : [Tuberculosis]·R E Chaisson
Oct 27, 1994·Nature·D AhmannF M Morel
Nov 1, 1993·Transactions of the Royal Society of Tropical Medicine and Hygiene·G K AmofahE H Frimpong
May 1, 1995·Clinics in Dermatology·F Portaels
Dec 1, 1996·Toxicology and Applied Pharmacology·C B Hartmann, K L McCoy
Feb 1, 1997·Tropical Medicine & International Health : TM & IH·P A FonteyneF Portaels
Jun 8, 1999·Journal of Medical Microbiology·P D JohnsonJ A Hayman
Jun 24, 1999·Environmental Health Perspectives·C O AbernathyM Waalkes
Aug 25, 1999·Lancet·F PortaelsW M Meyers
Sep 29, 1999·Lancet·T S van der WerfK Asiedu
Jul 27, 2001·Tropical Medicine & International Health : TM & IH·Y StienstraT S van der Werf
Mar 19, 2002·Emerging Infectious Diseases·George AmofahJonathan Addy
Aug 30, 2002·Applied and Environmental Microbiology·Laurent MarsollierBernard Carbonnelle
May 10, 2003·The Science of the Total Environment·M G M AlamA Tanaka
Jul 6, 2004·International Archives of Occupational and Environmental Health·J Alberto Rosales-CastilloEmma S Calderón-Aranda

❮ Previous
Next ❯

Citations

Nov 30, 2006·Advances in Skin & Wound Care·Thomas A Kwyer, Edwin Ampadu
Jan 1, 2012·Infectious Diseases of Poverty·Mercy M AckumeyMitchell G Weiss
Nov 4, 2008·Emerging Infectious Diseases·Kapay KibadiFrançoise Portaels
May 29, 2008·International Journal of Health Geographics·Tyler WagnerR Christian Johnson
Aug 13, 2015·International Journal of Environmental Research and Public Health·Mozhgon RajaeeNiladri Basu
Dec 15, 2017·Clinical Microbiology Reviews·Dezemon ZingueMichel Drancourt
Oct 17, 2015·PLoS Neglected Tropical Diseases·Lindsay P CampbellJiaguo Qi
Dec 24, 2010·PLoS Neglected Tropical Diseases·Richard W MerrittDaniel A Boakye
Jul 31, 2008·PLoS Neglected Tropical Diseases·Télesphore BrouJean-François Guegan
Feb 4, 2012·PLoS Neglected Tropical Diseases·Heather R WilliamsonPamela L C Small
Feb 3, 2011·Risk Analysis : an Official Publication of the Society for Risk Analysis·Chung-Min LiaoSzu-Chieh Chen
Jun 20, 2015·PLoS Neglected Tropical Diseases·Jianyong WuErica A H Smithwick
Apr 23, 2020·Interdisciplinary Perspectives on Infectious Diseases·Felix Okoe MettleClement Twumasi
Jul 20, 2010·Transactions of the Royal Society of Tropical Medicine and Hygiene·M Venkata RaghavaV Rajshekhar
Apr 15, 2016·PLoS Neglected Tropical Diseases·Kobina Assan AmpahDorothy Yeboah-Manu

❮ Previous
Next ❯

Methods Mentioned

BETA
amputation

Software Mentioned

ILWIS
ILWIS ( Integrated Land and Water Information Systems )

Related Feeds

Buruli Ulcer

Buruli ulcer is a progressive disease of subcutaneous tissues caused by mycobacterium ulcerans. Here is the latest research.