PMID: 8945064Nov 1, 1996Paper

Spatial distribution of QT intervals: an alternative approach to QT dispersion

Pacing and Clinical Electrophysiology : PACE
P Van LeeuwenM Wehr

Abstract

QT dispersion (QTd) describes the heterogeneity of ventricular repolarization on the basis of the temporal range of QT intervals as measured in the 12-lead ECG. We examined the spatial distribution of QTd using multichannel magnetocardiograms (MCGs), which noninvasively register changes in magnetic field strength at 37 sites over the heart. As in ECG, the MCG signal in each channel may be used to measure QT interval. By calculating QT deviation from QTmin at each site, one can reconstruct the spatial distribution of QTd. Analysis of spatial QTd in ten healthy subjects and ten patients after acute myocardial infarction (MI) showed clear differences in spatial distribution. The healthy subjects generally displayed shorter QT intervals along a line corresponding to the approximate position of the septum with longer intervals in plateaus in the upper right and lower left. Spatial QTd of the post-MI patients deviated from this pattern, often displaying a sharp rise in QT duration over specific areas, which could be related to functional and morphological disturbances. The quantification of local irregularities as well as the overall pattern on the basis of a smoothness index allowed better discrimination between healthy subjects and...Continue Reading

References

Jan 1, 1988·The American Journal of Cardiology·J C CowanR W Campbell
Aug 1, 1984·Journal of the American College of Cardiology·B Surawicz, S B Knoebel
Jan 1, 1980·British Heart Journal·J R MilneR A Spurrell
Sep 15, 1994·The American Journal of Cardiology·W ZarebaS le Cessie
Jan 1, 1996·Journal of the American College of Cardiology·J MolnarJ E Rosenthal
Feb 1, 1996·The American Journal of Cardiology·F BogunF Morady

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Citations

Sep 1, 1997·Herzschrittmachertherapie & Elektrophysiologie·H D Esperer
Sep 1, 1997·Herzschrittmachertherapie & Elektrophysiologie·H D Esperer
Sep 1, 1997·Herzschrittmachertherapie & Elektrophysiologie·B Hailer
Jun 7, 2005·Expert Review of Molecular Diagnostics·Riccardo FeniciAnna Maria Meloni
Jul 19, 2006·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Helena HänninenLauri Toivonen
Feb 13, 1999·Journal of Electrocardiology·K W LeeG E Dower
Aug 19, 2006·Biomedizinische Technik. Biomedical Engineering·Peter Van LeeuwenDietrich H W Grönemeyer
Nov 19, 2003·Pacing and Clinical Electrophysiology : PACE·Fiona E SmithAlan Murray
Jan 21, 2000·Pacing and Clinical Electrophysiology : PACE·G StroinkM J Gardner
Dec 24, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Donatella BrisindaRiccardo Fenici
Apr 10, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Robert FischerAlexander Schirdewan
Jul 14, 2006·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Fiona E SmithAlan Murray
Dec 22, 1998·Biomedizinische Technik. Biomedical Engineering·T GieslerW G Daniel
Jul 25, 2003·Pacing and Clinical Electrophysiology : PACE·Peter Van LeeuwenDietrich Grönemeyer

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